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Substance Name: Lemborexant [USAN:INN]
RN: 1369764-02-2
UNII: 0K5743G68X
InChIKey: MUGXRYIUWFITCP-PGRDOPGGSA-N

Note

  • A novel dual orexin receptor antagonist.

Molecular Formula

  • C22-H20-F2-N4-O2

Molecular Weight

  • 410.422
 

Classification Codes

  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Hypnotics and Sedatives
  • Neurotransmitter Agents
  • Orexin Receptor Antagonists
  • Sleep Aids, Pharmaceutical
  • Treatment of Insomnia
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Names and Synonyms

Name of Substance

  • Lemborexant [USAN:INN]

Synonyms

  • (1R,2S)-2-(((2,4-dimethyl-5-pyrimidinyl)oxy)methyl)-2-(3-fluorophenyl)-N-(5-fluoro-2-pyridinyl)cyclopropanecarboxamide
  • Cyclopropanecarboxamide, 2-(((2,4-dimethyl-5-pyrimidinyl)oxy)methyl)-2-(3-fluorophenyl)-N-(5-fluoro-2-pyridinyl)-, (1R,2S)-
  • Dayvigo
  • E 2006
  • Lemborexant
  • UNII-0K5743G68X

Registry Numbers

CAS Registry Number

  • 1369764-02-2

FDA UNII

  • 0K5743G68X

System Generated Number

  • 1369764022

Structure Descriptors

InChI

InChI=1S/C22H20F2N4O2/c1-13-19(11-25-14(2)27-13)30-12-22(15-4-3-5-16(23)8-15)9-18(22)21(29)28-20-7-6-17(24)10-26-20/h3-8,10-11,18H,9,12H2,1-2H3,(H,26,28,29)/t18-,22+/m0/s1

InChIKey

MUGXRYIUWFITCP-PGRDOPGGSA-N

Smiles

Cc1ncc(OC[C@]2(C[C@H]2C(=O)Nc3ccc(F)cn3)c4cccc(F)c4)c(C)n1