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Substance Name: Dextrothyroxine sodium [INN]
RN: 137-53-1
UNII: J60FX7V025
InChIKey: YDTFRJLNMPSCFM-UTONKHPSSA-M

Note

  • The dextrorotary isomer of the synthetic THYROXINE.

Molecular Formula

  • C15-H11-I4-N-O4.Na

Molecular Weight

  • 798.837
 

Classification Codes

  • Hormone
  • Human Data
  • Reproductive Effect
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Names and Synonyms

Results Name

  • Dextrothyroxine sodium [INN]

Name of Substance

  • Dextrothyroxine sodium anhydrous
  • Dextrothyroxine sodium [INN]

Synonyms

  • 3,3',5,5'-Tetraiodo-d-thyronine, sodium salt
  • 3:5:3':5'-Tetraiodo-D-thyronine sodium
  • Biotirmone
  • Choloxin
  • D-T4 sodium
  • D-Thyroxine sodium salt
  • Debetrol
  • Destrotirossina sodica
  • Destrotirossina sodica [DCIT]
  • Dethyrona
  • Detyroxin
  • Dextroid
  • Dextrothyroxine sodique
  • Dextrothyroxine sodique [INN-French]
  • Dextrothyroxine sodium
  • Dextrothyroxinum natricum
  • Dextrothyroxinum natricum [INN-Latin]
  • Dextrotiroxina sodica
  • Dextrotiroxina sodica [INN-Spanish]
  • Dextroxin
  • Dynothel
  • EINECS 205-301-2
  • Lisolipin
  • Nadrothyron D
  • Sodium D-3,3',5,5'-tetraiodothyronine
  • Sodium d-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)alanine
  • Sodium D-T4
  • Sodium D-thyroxine
  • Sodium dextrothyroxine
  • Sodium-D-thyroxine
  • Thyroxine monosodium salt, D-
  • Thyroxine, monosodium salt, D-
  • Travenon
  • UNII-J60FX7V025

Systematic Names

  • D-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt (9CI)
  • Dextrothyroxine sodium
  • Thyroxine, monosodium salt, D-

Registry Numbers

CAS Registry Number

  • 137-53-1

FDA UNII

  • J60FX7V025

Other Registry Number

  • 7548-09-6

System Generated Number

  • 0000137531

Molecular Formulas

Molecular Formula

  • C15-H11-I4-N-O4.Na

Molecular Formula Fragments

  • C15-H11-I4-N-O4
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/q;+1/p-1/t12-;/m1./s1

InChIKey

YDTFRJLNMPSCFM-UTONKHPSSA-M

Smiles

[Na+].N[C@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(=O)[O-]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo oral 12ug/kg/12D-I (0.012mg/kg) LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), DIFFUSE"

LIVER: LIVER FUNCTION TESTS IMPAIRED
Japanese Journal of Medicine. Vol. 23, Pg. 282, 1984.