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Substance Name: Otlertuzumab [USAN:INN]
RN: 1372645-37-8
UNII: 2MZ3L2664T


  • An anti-CD37 IgG fusion protein for treating B-cell malignancies.

Molecular Formula

  • C4660-H7136-N1246-O1452-S30

Classification Code

  • Antineoplastic
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Names and Synonyms

Name of Substance

  • Otlertuzumab [USAN:INN]


  • Immunoglobulin G1-kappa single chain fragment, anti-(human leukocyte antigen CD37 (tetraspanin-26)), humanized mouse monoclonal antibody; single chain (1-483) (humanized VH (Homo sapiens IGHV5-a*04 (84.7%)-(IGHD)-IGHJ5*01) (8.8.9) (1-116) linker pentakis(tetraglycyl-L-seryl) (117-141) humanized V-KAPPA (Homo sapiens IGKV3-11*01 (84.7%)-IGKJ1*01) (6.3.9) (142-248) glycyl-L-aspartyl-L-glutaminyl-(5-L-serineH5C>S(256),11-L-serineH11C>S(262))Homo sapiens IGHG1 Fc fragment (249-483)); dimer (265-265')-disulfide
  • Otlertuzumab
  • TRU 016
  • TRU-016
  • UNII-2MZ3L2664T

Systematic Name

  • Immunoglobulin, anti-(human CD antigen CD37) (synthetic human-Mus musculus fragment TRU-016), dimer

Registry Numbers

CAS Registry Number

  • 1372645-37-8


  • 2MZ3L2664T

System Generated Number

  • 1372645378