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Substance Name: dl-Norepinephrine
RN: 138-65-8
UNII: K294OAI79V
InChIKey: SFLSHLFXELFNJZ-UHFFFAOYSA-N

Molecular Formula

  • C8-H11-N-O3

Molecular Weight

  • 169.1789
 
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Names and Synonyms

Results Name

  • dl-Norepinephrine

Name of Substance

  • Norepinephrine, DL-

Synonyms

  • (+-)-Noradrenaline
  • 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-
  • dl-Arterenol
  • dl-Norepinephrine
  • EINECS 205-337-9
  • Noradrenalin, dl-
  • NSC 294898
  • UNII-K294OAI79V

Systematic Names

  • (1)-4-(2-Amino-1-hydroxyethyl)pyrocatechol
  • 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (+-)- (9CI)
  • Benzyl alcohol, alpha-(aminomethyl)-3,4-dihydroxy-, (+-)-

Registry Numbers

CAS Registry Number

  • 138-65-8

FDA UNII

  • K294OAI79V

System Generated Number

  • 0000138658

Structure Descriptors

InChI

1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,9H2

InChIKey

SFLSHLFXELFNJZ-UHFFFAOYSA-N

Smiles

NCC(O)c1ccc(O)c(O)c1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 15600ug/kg (15.6mg/kg)   Proceedings of the Society for Experimental Biology and Medicine. Vol. 68, Pg. 501, 1948.
mouse LD50 intravenous 4700ug/kg (4.7mg/kg) KIDNEY, URETER, AND BLADDER: "INFLAMMATION, NECROSIS, OR SCARRING OF BLADDER"

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA

LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 502, 1949.
mouse LD50 subcutaneous 40mg/kg (40mg/kg)   "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948Vol. -, Pg. 64, 1948.
rat LD50 intravenous 130ug/kg (0.13mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 502, 1949.
rat LD50 subcutaneous > 2mg/kg (2mg/kg)   Proceedings of the Society for Experimental Biology and Medicine. Vol. 68, Pg. 501, 1948.