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Substance Name: 2,3-Diphosphoglycerate
RN: 138-81-8
UNII: TZ4454O4YZ
InChIKey: XOHUEYCVLUUEJJ-UHFFFAOYSA-N
Note
- A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
Molecular Formula
- C3-H8-O10-P2
Molecular Weight
- 266.0342
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Names and Synonyms
Name of Substance
- 2,3-Diphosphoglycerate
MeSH Heading
- 2,3-Diphosphoglycerate
Synonyms
- 2,3-Bisphosphoglycerate
- 2,3-Diphosphoglycerate
- 2,3-Diphosphoglyceric acid
- 2,3-Dpg
- UNII-TZ4454O4YZ
Systematic Name
- Propanoic acid, 2,3-bis(phosphonooxy)-
Registry Numbers
CAS Registry Number
- 138-81-8
FDA UNII
- TZ4454O4YZ
System Generated Number
- 0000138818