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Substance Name: Leteprinim [INN]
RN: 138117-50-7
UNII: NBY3IU407M
InChIKey: JMPOIZCOJJMTHI-UHFFFAOYSA-N
Note
- A neuroprotective agent that has been shown to improve memory; induces NGF-dependent nociceptive nerve sprouting.
Molecular Formula
- C15-H13-N5-O4
Molecular Weight
- 327.2987
Classification Code
- Drug / Therapeutic Agent
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Names and Synonyms
Results Name
- Leteprinim [INN]
Name of Substance
- 4-((3-(1,6-Dihyro-6-oxo-9H-purin-9-yl)-1-oxopropyl)amino)benzoic acid
- Leteprinim [INN]
Synonyms
- 4-((3-(1,6-Dihydro-6-oxo-9H-purin-9-yl)-1-oxopropyl)amino)benzoic acid
- AIT 082
- AIT 082 acid
- Leteprinim
- N-(4-Carboxyphenyl)-3-(6-oxohydropurin-9-yl)propanamide
- p-(3-(1,6-Dihydro-6-oxo-9H-purin-9-yl)propionamido)benzoic acid
- UNII-NBY3IU407M
Systematic Name
- Benzoic acid, 4-((3-(1,6-dihydro-6-oxo-9H-purin-9-yl)-1-oxopropyl)amino)-
Registry Numbers
CAS Registry Number
- 138117-50-7
FDA UNII
- NBY3IU407M
System Generated Number
- 0138117507
Structure Descriptors
InChI
1S/C15H13N5O4/c21-11(19-10-3-1-9(2-4-10)15(23)24)5-6-20-8-18-12-13(20)16-7-17-14(12)22/h1-4,7-8H,5-6H2,(H,19,21)(H,23,24)(H,16,17,22)InChIKey
JMPOIZCOJJMTHI-UHFFFAOYSA-NSmiles
c1cc(ccc1C(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | > 3gm/kg (3000mg/kg) | United States Patent Document. Vol. #5447939, | |
mouse | LD50 | oral | > 3gm/kg (3000mg/kg) | United States Patent Document. Vol. #5447939, | |
rat | LD50 | intraperitoneal | > 3gm/kg (3000mg/kg) | United States Patent Document. Vol. #5447939, | |
rat | LD50 | oral | > 3gm/kg (3000mg/kg) | United States Patent Document. Vol. #5447939, |