Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Cimadronate
RN: 138330-18-4
UNII: 7L16W0096A
InChIKey: RLIRIVMEKVNVQX-UHFFFAOYSA-L

Note

  • Increases serum 1,25-dihydroxyvitamin D in rats via stimulating renal 1-hydroxylase activity.

Molecular Formula

  • C8-H19-N-O6-P2.2Na

Molecular Weight

  • 330.1632
 

Classification Codes

  • Bone Density Conservation Agents
  • Drug / Therapeutic Agent
  • Reproductive Effect
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Cimadronate

Synonyms

  • Cimadronate
  • Disodium cycloheptylaminomethylenediphosphonate
  • UNII-7L16W0096A
  • YM 175
  • YM-175

Systematic Name

  • Phosphonic acid, ((cycloheptylamino)methylene)bis-, disodium salt

Registry Numbers

CAS Registry Number

  • 138330-18-4

FDA UNII

  • 7L16W0096A

System Generated Number

  • 0138330184

Molecular Formulas

Molecular Formula

  • C8-H19-N-O6-P2.2Na

Molecular Formula Fragments

  • C8-H19-N-O6-P2
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C9H20O6P2.2Na/c10-16(11,12)9(17(13,14)15)7-8-5-3-1-2-4-6-8;;/h8-9H,1-7H2,(H2,10,11,12)(H2,13,14,15);;/q;2*+1/p-2

InChIKey

RLIRIVMEKVNVQX-UHFFFAOYSA-L

Smiles

C1CCCC(CC1)CC(P(=O)(O)[O-])P(=O)(O)[O-].[Na+].[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD intravenous > 10mg/kg (10mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Toxicological Sciences. Vol. 20(Suppl,
mouse LD50 intravenous 16mg/kg (16mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 684, 1998.
rat LD50 intravenous 21mg/kg (21mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Journal of Toxicological Sciences. Vol. 20(Suppl,