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Substance Name: Growth differentiation factor 1
RN: 138391-30-7


  • A growth differentiation factor that plays a role in the genesis of left-right asymmetry during vertebrate development. Evidence for this role is seen in MICE where loss of growth differentiation factor 1 function results in right-left isomerism of visceral organs. In HUMANS heterozygous loss of growth differentiation factor 1 function has been associated with CONGENITAL HEART DEFECTS and TRANSPOSITION OF GREAT VESSELS.
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Names and Synonyms

Name of Substance

  • Growth differentiation factor 1

MeSH Heading

  • Growth differentiation factor 1


  • GDF-1

Systematic Name

  • Protein (human clone hBr-3 gene GDF-1 reduced)

Registry Numbers

CAS Registry Number

  • 138391-30-7

System Generated Number

  • 0138391307