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Substance Name: Activin receptor
RN: 138391-53-4

Note

  • Receptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREONINE KINASES, thus also named activin receptor-like kinases (ALK's). Activin receptors also bind TRANSFORMING GROWTH FACTOR BETA. As those transmembrane receptors of the TGF-beta superfamily (RECEPTORS, TRANSFORMING GROWTH FACTOR BETA), ALK's consist of two different but related protein kinases, Type I and Type II. Activins initiate cellular signal transduction by first binding to the type II receptors (ACTIVIN RECEPTORS, TYPE II ) which then recruit and phosphorylate the type I receptors (ACTIVIN RECEPTORS, TYPE I ) with subsequent activation of the type I kinase activity.
 
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Names and Synonyms

Name of Substance

  • Activin receptor

MeSH Heading

  • Activin Receptors

Synonyms

  • Activin receptor
  • Activin receptor type IIb
  • Activin receptors
  • Punt gene product
  • Receptor, activin

Systematic Name

  • Receptor, activin (mouse clone pmActR2 protein moiety reduced)

Registry Numbers

CAS Registry Number

  • 138391-53-4

System Generated Number

  • 0138391534