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Substance Name: Aducanumab [USAN:INN]
RN: 1384260-65-4
UNII: 105J35OE21

Note

  • MAB against Amyloid beta-Peptide for treatment of Alzheimer Disease.

Molecular Formula

  • C6472-H10028-N1740-O2014-S46
 

Classification Code

  • Treatment of Alzheimer's Disease
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Links to Resources

Names and Synonyms

Name of Substance

  • Aducanumab [USAN:INN]

Synonyms

  • Aducanumab
  • BIIB 037
  • BIIB-037
  • BIIB037
  • Immunoglobulin G1-kappa, anti-(human amyloid beta A4 protein(ABPP, APPI, Alzheimer disease amyloid protein, cerebral vascular amyloid peptide, protease nexin-II)), Homo sapiens monoclonal antibody; gamma 1 heavy chain (1-453) (Homo sapiens VH (IGHV3-33*01 Q1>pyroGlu(1) (93.9%)-(IGHD)-IGHJ6*03) (8.8.17) (1-124)-IGHG1*03 des-CH3K107 (125-453)), (227-214')-disulfide with kappa light chain (1'-214') (Homo sapiens V-KAPPA (IGKV1D-39*01 (100%)-IGKJ4*01) (6.3.9) (1'-107')-IGKC*01 (108'-214')); dimer (233-233'':236-236'')-bisdisulfide
  • UNII-105J35OE21

Systematic Name

  • Immunoglobulin G1, anti-(human beta-amyloid) (human monoclonal BIIB037 heavy chain), disulfide with human monoclonal BIIB037 kappa-chain, dimer

Registry Numbers

CAS Registry Number

  • 1384260-65-4

FDA UNII

  • 105J35OE21

System Generated Number

  • 1384260654