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Substance Name: BFRF1 protein, Human herpesvirus 4
RN: 138880-50-9


  • A fibroblast growth factor receptor that is found in two isoforms. One receptor isoform is found in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform of fibroblast growth factor receptor 2 is found mainly in EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).
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Names and Synonyms

Name of Substance

  • BFRF1 protein, Human herpesvirus 4

MeSH Heading

  • Receptor, Fibroblast Growth Factor, Type 2


  • Bek related fibroblast growth factor receptors-1
  • Bek-related fibroblast growth factor-receptor-1
  • Bfr-1 gene product
  • Receptor-1, bek-related fibroblast growth factor

Systematic Name

  • Receptor, fibrolbast growth factor (human clone pTB1284 isoform 1 precursor protein moiety reduced)

Registry Numbers

CAS Registry Number

  • 138880-50-9

System Generated Number

  • 0138880509