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Substance Name: Grisein
RN: 1391-82-8

Note

  • From Streptomyces griseus.

Molecular Formula

  • C40-H61-Fe-N10-O20-S
 

Classification Codes

  • Drug / Therapeutic Agent
  • Natural Product
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Links to Resources

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Names and Synonyms

Name of Substance

  • Grisein

Synonyms

  • Albomycin A1
  • Cormogrizin
  • Kormogrizein

Systematic Name

  • Grisein

Registry Numbers

CAS Registry Number

  • 1391-82-8

System Generated Number

  • 0001391828

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 600mg/kg (600mg/kg)   "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(1), Pg. 442, 1980.
mouse LD50 oral 600mg/kg (600mg/kg)   Merck Index. Vol. 10, Pg. 653, 1983.
mouse LD50 subcutaneous 34mg/kg (34mg/kg)   Merck Index. Vol. 10, Pg. 653, 1983.
rabbit LDLo oral 1gm/kg (1000mg/kg) LIVER: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

BLOOD: HEMORRHAGE
Veterinariya. Veterinary Science. Vol. 51(12), Pg. 93, 1974.
rabbit LDLo subcutaneous 25mg/kg (25mg/kg) LIVER: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"

BLOOD: HEMORRHAGE
Veterinariya. Veterinary Science. Vol. 51(12), Pg. 93, 1974.