Substance Name: Grisein
RN: 1391-82-8
Note
- From Streptomyces griseus.
Molecular Formula
- C40-H61-Fe-N10-O20-S
Classification Codes
- Drug / Therapeutic Agent
- Natural Product
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Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- Grisein
Synonyms
- Albomycin A1
- Cormogrizin
- Kormogrizein
Systematic Name
- Grisein
Registry Numbers
CAS Registry Number
- 1391-82-8
System Generated Number
- 0001391828
Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 600mg/kg (600mg/kg) | "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(1), Pg. 442, 1980. | |
| mouse | LD50 | oral | 600mg/kg (600mg/kg) | Merck Index. Vol. 10, Pg. 653, 1983. | |
| mouse | LD50 | subcutaneous | 34mg/kg (34mg/kg) | Merck Index. Vol. 10, Pg. 653, 1983. | |
| rabbit | LDLo | oral | 1gm/kg (1000mg/kg) | LIVER: OTHER CHANGES KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" BLOOD: HEMORRHAGE | Veterinariya. Veterinary Science. Vol. 51(12), Pg. 93, 1974. |
| rabbit | LDLo | subcutaneous | 25mg/kg (25mg/kg) | LIVER: OTHER CHANGES KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" BLOOD: HEMORRHAGE | Veterinariya. Veterinary Science. Vol. 51(12), Pg. 93, 1974. |