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Substance Name: Fusafungine [INN:BAN:DCF]
RN: 1393-87-9
UNII: 65DD690W0C
InChIKey: MIZMDSVSLSIMSC-OGLSAIDSSA-N

Note

  • Antibiotic from Fusarium lateririum; for treatment of respiratory infections.

Molecular Formula

  • C29-H51-N2-O8

Molecular Weight

  • 639.8253
 

Classification Codes

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Drug / Therapeutic Agent
  • Natural Product
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Names and Synonyms

Name of Substance

  • Fusafungin
  • Fusafungine [INN:BAN:DCF]

Synonyms

  • Biofusal
  • Bioparox
  • Bioparox spray
  • EINECS 215-737-5
  • Fusafungin
  • Fusafungina
  • Fusafungina [INN-Spanish]
  • Fusafungine
  • Fusafunginum
  • Fusafunginum [INN-Latin]
  • Fusaloyos
  • Fusarine
  • Locabiotal
  • S 314
  • UNII-65DD690W0C

Systematic Names

  • Antibiotic obtained from cultures of a fusarium belonging to Lateritium Wr. section, or the same substance produced by any other means
  • Fusafungine

Registry Numbers

CAS Registry Number

  • 1393-87-9

FDA UNII

  • 65DD690W0C

System Generated Number

  • 0001393879

Structure Descriptors

InChI

1S/C33H57N3O9/c1-16(2)22-31(40)43-26(20(9)10)29(38)35(14)24(18(5)6)33(42)45-27(21(11)12)30(39)36(15)23(17(3)4)32(41)44-25(19(7)8)28(37)34(22)13/h16-27H,1-15H3/t22-,23-,24-,25?,26?,27?/m0/s1

InChIKey

MIZMDSVSLSIMSC-OGLSAIDSSA-N

Smiles

CC(C)C1OC(=O)[C@H](C(C)C)N(C)C(=O)C(OC(=O)[C@H](C(C)C)N(C)C(=O)C(OC(=O)[C@H](C(C)C)N(C)C1=O)C(C)C)C(C)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 oral 350mg/kg (350mg/kg)   "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 4(2), Pg. 182, 1980.