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Substance Name: NF-kappaB inhibitor alpha
RN: 139874-52-5


  • An I-kappa B protein that inhibits the activity of dimeric NF-KAPPA B P50-REL complexes, sequesters transcription factor NF-kappaB as an inactive complex in the cytoplasm; and prevents NF-kappaB nuclear translocation and DNA binding.
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Names and Synonyms

Name of Substance

  • NF-kappaB inhibitor alpha

MeSH Heading

  • NF-KappaB Inhibitor alpha


  • Edg-3 gene product
  • Edg-3 protein
  • I kappa B-alpha Protein
  • Ikappab-alpha
  • Ikappabalpha
  • Mad3 inhibitor
  • p40 Protein (ikappab-alpha)

Systematic Name

  • Protein (human clone MAD-3 gene MAD-3 reduced)

Registry Numbers

CAS Registry Number

  • 139874-52-5

System Generated Number

  • 0139874525