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Substance Name: ME-3221
RN: 139958-16-0
InChIKey: FTDRSCZZEUAAIP-UHFFFAOYSA-N

Note

  • An angiotensin II receptor antagonist.

Molecular Weight

  • 387.441
 
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Names and Synonyms

Results Name

  • ME-3221

Synonyms

  • 3-Methoxy-2,6-dimethyl-4-(2'-(1H-tetrazol-5-yl) biphenyl-4-ylmethoxy)pyridine
  • ME 3221

Registry Numbers

CAS Registry Number

  • 139958-16-0

System Generated Number

  • 0139958160

Structure Descriptors

InChI

1S/C22H21N5O2/c1-14-12-20(21(28-3)15(2)23-14)29-13-16-8-10-17(11-9-16)18-6-4-5-7-19(18)22-24-26-27-25-22/h4-12H,13H2,1-3H3,(H,24,25,26,27)

InChIKey

FTDRSCZZEUAAIP-UHFFFAOYSA-N

Smiles

c1(c(c(cc(n1)C)OCc1ccc(cc1)c1c(cccc1)c1nnn[nH]1)OC)C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 oral 2gm/kg (2000mg/kg)   Cardiovascular Drug Reviews. Vol. 15, Pg. 291, 1997.