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Substance Name: Pramocaine [INN:BAN]
RN: 140-65-8
UNII: 068X84E056
InChIKey: DQKXQSGTHWVTAD-UHFFFAOYSA-N

Classification Codes

  • Anesthetics
  • Anesthetics, Local
  • Central Nervous System Agents
  • Central Nervous System Depressants
  • Peripheral Nervous System Agents
  • Sensory System Agents

Molecular Formula

  • C17-H27-N-O3

Molecular Weight

  • 293.404
 

Names and Synonyms

Name of Substance

  • Pramocaine [INN:BAN]
  • Pramoxine

Synonyms

  • 4-(3-(p-Butoxyphenoxy)propyl)morpholine
  • 4-27-00-00127 (Beilstein Handbook Reference)
  • BRN 0239059
  • EINECS 205-425-7
  • gamma-Morpholinopropyl 4-n-butoxyphenyl ether
  • p-Butoxyphenyl gamma-morpholinopropyl ether
  • Pramocaina
  • Pramocaina [INN-Spanish]
  • Pramocaine
  • Pramocainum
  • Pramocainum [INN-Latin]
  • Pramoxine
  • Proxazocain
  • Tronopthane
  • Tronothane
  • UNII-068X84E056

Systematic Names

  • Morpholine, 4-(3-(p-butoxyphenoxy)propyl)-
  • Pramocaine

Registry Numbers

CAS Registry Number

  • 140-65-8

FDA UNII

  • 068X84E056

Related Registry Number

  • 637-58-1 (hydrochloride)

System Generated Number

  • 0000140658

Structure Descriptors

InChI

1S/C17H27NO3/c1-2-3-12-20-16-5-7-17(8-6-16)21-13-4-9-18-10-14-19-15-11-18/h5-8H,2-4,9-15H2,1H3

InChIKey

DQKXQSGTHWVTAD-UHFFFAOYSA-N

Smiles

c1(ccc(OCCCC)cc1)OCCCN1CCOCC1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 300mg/kg (300mg/kg)   Anesthesia and Analgesia Vol. 38, Pg. 265, 1959.
mouse LD50 intravenous 79mg/kg (79mg/kg)   European Journal of Medicinal Chemistry--Chimie Therapeutique. Vol. 10, Pg. 291, 1975.
mouse LD50 subcutaneous 900mg/kg (900mg/kg)   Anesthesia and Analgesia Vol. 38, Pg. 265, 1959.

Physical Properties

Physical Property Value Units Temp (deg C) Source
log P (octanol-water) 3.430 (none)   EST
Atmospheric OH Rate Constant 1.93E-10 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.