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Substance Name: SL 6057
RN: 14008-79-8
InChIKey: FXKCQWIUITUJFU-UHFFFAOYSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C21-H24-Cl-N-O.Cl-H

Molecular Weight

  • 378.341
 
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Names and Synonyms

Results Name

  • SL 6057

Synonyms

  • 3-alpha-((p-Chloro-alpha-phenylbenzyl)oxy)-1-alpha-H,5-alpha-H-tropane hydrochloride
  • Chlortropbenzyl
  • FC-1
  • SL-6057
  • Tropine 4-chlorobenzhydryl ether hydrochloride
  • WY 2149

Systematic Name

  • 1-alpha-H,5-alpha-H-Tropane, 3-alpha-((p-chloro-alpha-phenylbenzyl)oxy)-, hydrochloride

Registry Numbers

CAS Registry Number

  • 14008-79-8

System Generated Number

  • 0014008798

Molecular Formulas

Molecular Formula

  • C21-H24-Cl-N-O.Cl-H

Molecular Formula Fragments

  • C21-H24-Cl-N-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C21H24ClNO.ClH/c1-23-18-11-12-19(23)14-20(13-18)24-21(15-5-3-2-4-6-15)16-7-9-17(22)10-8-16;/h2-10,18-21H,11-14H2,1H3;1H

InChIKey

FXKCQWIUITUJFU-UHFFFAOYSA-N

Smiles

C1[C@@H]2CC[C@@H](CC1O[C@@H](c1ccccc1)c1ccc(cc1)Cl)N2C.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 28mg/kg (28mg/kg) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Pharmacology and Experimental Therapeutics. Vol. 114, Pg. 192, 1955.
mouse LD50 intraperitoneal 32mg/kg (32mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: TREMOR
Journal of Pharmacology and Experimental Therapeutics. Vol. 114, Pg. 192, 1955.
mouse LD50 oral 174mg/kg (174mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: ATAXIA

BEHAVIORAL: MUSCLE WEAKNESS
Journal of Pharmacology and Experimental Therapeutics. Vol. 114, Pg. 192, 1955.
rat LD50 intraperitoneal 58mg/kg (58mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: ATAXIA
Journal of Pharmacology and Experimental Therapeutics. Vol. 114, Pg. 192, 1955.
rat LD50 oral 364mg/kg (364mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: ATAXIA

BEHAVIORAL: MUSCLE WEAKNESS
Journal of Pharmacology and Experimental Therapeutics. Vol. 114, Pg. 192, 1955.