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Substance Name: Pentosan polysulfate sodium [USAN:INN:BAN]
RN: 140207-93-8
UNII: 914032762Y

Note

  • A sulfated pentosyl polysaccharide with heparin-like properties.

Molecular Formula

  • (C5-H6-Na2-O10-S2)mult-

Molecular Weight

  • 336.204
 

Classification Codes

  • Anti-Inflammatory (Interstitial Cystitis)
  • Anticoagulants
  • Drug / Therapeutic Agent
  • Hematologic Agents
  • Human Data

Names and Synonyms

Name of Substance

  • HOE-BAY 946
  • Pentosan polysulfate sodium [USAN:INN:BAN]

Synonyms

  • (4-O-Methyl-alpha-D-glucurono)-(1-2)-(1-4)-beta-D-xylopyranan, hydrogen sulfate, sodium salt
  • 4-O-Methyl-alpha-D-glucurono-beta-D-xylan, hydrogen sulfate, sodium salt
  • Cartrophen
  • CB 8061
  • Elmiron
  • Fibrezym
  • Hemoclar
  • Hemoclar [French]
  • HOE/BAY 946
  • Pentosan polysulfate sodium
  • Pentosan sulfate
  • PPS
  • PZ 68
  • PZ68
  • Sodium pentosan polysulfate
  • SP 54
  • SP54
  • Tavan SP 54
  • Thrombocid
  • UNII-914032762Y

Systematic Names

  • 4-O-Methyl-alpha-D-glucurono-beta-D-xylan, hydrogen sulfate, sodium salt
  • beta-D-Xylan, (1-4), 2,3-bis(hydrogen sulfate), sodium salt

Registry Numbers

CAS Registry Number

  • 140207-93-8

FDA UNII

  • 914032762Y

Other Registry Number

  • 116001-96-8

System Generated Number

  • 0140207938

Molecular Formulas

Molecular Formula

  • (C5-H6-Na2-O10-S2)mult-

Molecular Formula Fragments

  • C5-H6-Na2-O10-S2
  • COMPONENT

Structure Descriptors

Smiles

O1C[C@@H](O*)[C@H](OS(=O)(=O)[O-])[C@H]([C@@H]1*)OS(=O)([O-])=O.[Na+].[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo unreported 48mg/kg/8D-I (48mg/kg) BLOOD: THROMBOCYTOPENIA

VASCULAR: THROMBOSIS DISTANT FROM INJECTION SITE
Therapie. Vol. 45, Pg. 514, 1990.