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Substance Name: Hamycin [USAN:INN]
RN: 1403-71-0

Note

  • Conjugated heptaene isolated from Streptomyces pimprina; used in blastomycosis and candidiasis; JAI-HA is water soluble and contains 1/25th of the parent drug by weight.

Molecular Formula

  • Unspecified
 

Classification Codes

  • Anti-Infective Agents
  • Antifungal
  • Antifungal Agents
  • Antiparasitic Agents
  • Antiprotozoal Agents
  • Drug / Therapeutic Agent
  • Natural Product
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Links to Resources

Names and Synonyms

Name of Substance

  • Hamycin
  • Hamycin [USAN:INN]

Synonyms

  • Hamicina
  • Hamicina [INN-Spanish]
  • Hamycin
  • Hamycine
  • Hamycine [French]
  • Hamycine [INN-French]
  • Hamycinum
  • Hamycinum [INN-Latin]
  • Primamycin

Systematic Name

  • Hamycin

Registry Numbers

CAS Registry Number

  • 1403-71-0

System Generated Number

  • 0001403710

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 2780ug/kg (2.78mg/kg)   Indian Journal of Medical Research. Vol. 51, Pg. 453, 1963.
mouse LD50 intraperitoneal 100ug/kg (0.1mg/kg)   Indian Journal of Pharmaceutical Sciences. Vol. 52, Pg. 227, 1990.
mouse LD50 intravenous 150ug/kg (0.15mg/kg)   Indian Journal of Pharmaceutical Sciences. Vol. 52, Pg. 227, 1990.
mouse LD50 oral 1200mg/kg (1200mg/kg)   "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 2, Pg. 258, 1980.
rat LD oral > 1200mg/kg (1200mg/kg)   Annales Pharmaceutiques Francaises. Vol. 23, Pg. 585, 1965.
rat LD subcutaneous > 100mg/kg (100mg/kg)   Annales Pharmaceutiques Francaises. Vol. 23, Pg. 585, 1965.
rat LDLo intravenous 1mg/kg (1mg/kg)   Annales Pharmaceutiques Francaises. Vol. 23, Pg. 585, 1965.