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Substance Name: alpha-Sarcin
RN: 1407-48-3


  • Isolated from aspergillus giganteus; sequence similarity with ribonucleases such as RIBONUCLEASE T1; 85% identity with restrictocin; a ribotoxin cleaving the phosphodiester bond on the 3' side of G4325 in the alpha-sarcin/ricin domain of rat 28S RIBOSOMAL RNA; sometimes called a ribosome-inactivating protein but falls outside the normal definition of plant RIP that de-adenylate rRNA.

Molecular Formula

  • Unspecified

Classification Codes

  • Enzyme Inhibitors
  • Protein Synthesis Inhibitors
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Names and Synonyms

Name of Substance

  • alpha-Sarcin


  • Ribosome-inactivating protein, aspergillus

Systematic Name

  • alpha-Sarcin (VAN)

Registry Numbers

CAS Registry Number

  • 1407-48-3

System Generated Number

  • 0001407483