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Substance Name: Ralpancizumab [USAN:INN]
RN: 1407495-04-8
UNII: YB9L51E4MD

Note

  • A PCSK9 inhibitor.

Molecular Formula

  • C6422-H9922-N1730-O2012-S54
 

Classification Code

  • Treatment of Dyslipidemia
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Names and Synonyms

Name of Substance

  • Ralpancizumab [USAN:INN]

Synonyms

  • PF-05335810
  • Ralpancizumab
  • RN317
  • UNII-YB9L51E4MD

Systematic Names

  • Immunoglobulin G2, anti-(human neural apoptosis-regulated proteinase 1)(human-Mus musculus monoclonal PF-05335810 heavy chain), disulfide with human-Mus musculus monoclonal PF-05335810 light chain, dimer
  • Immunoglobulin G2-kappa, anti-(human proprotein convertase subtilisin/hexin type 9 (neural apoptosis-regulated convertase 1, PC9)), humanized mouse monoclonal antibody; gamma 2 heavy chain (1-444) (humanized VH (Homo sapiens IGHV1-46*03 (91.8%) -(IGHD)-IGHJ6*01) (8.8.11) (1-118)-Homo sapiens IGHG2*01 CH2A100>S(327),CH2P101>S(328) (119-444)) (132-214')-disulfide with kappa light chain (1'-214') (humanized V-KAPPA (Homo sapiens IGKV1-33*01 (85.1%)-IGKJ1*01 120G>Q(100) (6.3.9) (1'-107')-IGKC*01 (108'-214')); dimer (220-220'':221-221'':224-224'':227-227'')-tetrakisdisulfide

Registry Numbers

CAS Registry Number

  • 1407495-04-8

FDA UNII

  • YB9L51E4MD

System Generated Number

  • 1407495048