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Substance Name: Ethyl acetate [NF]
RN: 141-78-6
UNII: 76845O8NMZ
InChIKey: XEKOWRVHYACXOJ-UHFFFAOYSA-N

Molecular Formula

  • C4-H8-O2

Molecular Weight

  • 88.1052
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Fungicide, Bactericide, Wood Preservative
  • Human Data
  • Mutation Data
  • Pharmaceutic Aid (Solvent)
  • Skin / Eye Irritant

Superlist Classification Codes

  • Reportable Quantity (RQ) = 5000 lb
  • TWA (400 ppm)
  • TWA 400 ppm (1400 mg/m3)

Names and Synonyms

Name of Substance

  • Acetic acid, ethyl ester
  • Ethyl acetate
  • Ethyl acetate [NF]

Synonyms

  • Acetate d'ethyle
  • Acetate d'ethyle [French]
  • Acetato de etilo
  • Acetato de etilo [Spanish]
  • Acetic acid, ethyl ester
  • Acetic ether
  • Acetidin
  • Acetoxyethane
  • Aethylacetat
  • Aethylacetat [German]
  • AI3-00404
  • Caswell No. 429
  • CCRIS 6036
  • EC 205-500-4
  • EINECS 205-500-4
  • EPA Pesticide Chemical Code 044003
  • Essigester
  • Essigester [German]
  • Ethyl acetate
  • Ethyl acetate (natural)
  • Ethyl acetic ester
  • Ethyl ester
  • Ethyl ethanoate
  • Ethylacetaat
  • Ethylacetaat [Dutch]
  • Ethylacetate
  • Ethyle (acetate d')
  • Ethyle (acetate d') [French]
  • Ethylester kyseliny octove
  • Ethylester kyseliny octove [Czech]
  • Etile (acetato di)
  • Etile (acetato di) [Italian]
  • FEMA No. 2414
  • HSDB 83
  • NSC 70930
  • Octan etylu
  • Octan etylu [Polish]
  • RCRA waste number U112
  • UNII-76845O8NMZ
  • Vinegar naphtha

Systematic Names

  • Acetic acid ethyl ester
  • Ethyl acetate

Superlist Names

  • Acetic acid ethyl ester
  • Acetic acid, ethyl ester
  • Ethyl acetate
  • Ethyl acetate [UN1173] [Flammable liquid]
  • RCRA waste no. U112
  • UN1173

Registry Numbers

CAS Registry Number

  • 141-78-6

FDA UNII

  • 76845O8NMZ

System Generated Number

  • 0000141786

Structure Descriptors

InChI

1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3

InChIKey

XEKOWRVHYACXOJ-UHFFFAOYSA-N

Smiles

O(C(=O)C)CC

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LCLo inhalation 61gm/m3 (61000mg/m3)   "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 1, Pg. 336, 1955.
cat LD50 subcutaneous 3gm/kg (3000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BLOOD: OTHER CHANGES

GASTROINTESTINAL: NAUSEA OR VOMITING
Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933.
guinea pig LD50 oral 5500mg/kg (5500mg/kg) BEHAVIORAL: COMA

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(4), Pg. 66, 1983.
guinea pig LD50 subcutaneous 3gm/kg (3000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 5, Pg. 1, 1933.
human TCLo inhalation 400ppm (400ppm) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE
Journal of Industrial Hygiene and Toxicology. Vol. 25, Pg. 282, 1943.
mouse LC50 inhalation 45gm/m3/2H (45000mg/m3)   "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 65, 1982.
mouse LD50 intraperitoneal 709mg/kg (709mg/kg)   Shell Chemical Company. Unpublished Report. Vol. -, Pg. 5, 1961.
mouse LD50 oral 4100mg/kg (4100mg/kg) BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: COMA
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(4), Pg. 66, 1983.
rabbit LD50 oral 4935mg/kg (4935mg/kg)   Industrial Medicine and Surgery. Vol. 41, Pg. 31, 1972.
rabbit LD50 skin > 20mL/kg (20mL/kg)   Union Carbide Data Sheet. Vol. 10/4/1968,
rat LC50 inhalation 200gm/m3 (200000mg/m3) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
Science Reports of the Research Institutes, Tohoku University, Series C: Medicine. Vol. 36(1-4), Pg. 10, 1989.
rat LD50 oral 5620mg/kg (5620mg/kg)   Yakkyoku. Pharmacy. Vol. 32, Pg. 1241, 1981.
rat LDLo subcutaneous 5gm/kg (5000mg/kg)   Bolletino della Societe Italiana di Biologia Sperimentale. Vol. 18, Pg. 45, 1943.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point -8.36E+01 deg C   EXP
Boiling Point 77.1 deg C   EXP
log P (octanol-water) 0.73 (none)   EXP
Water Solubility 8.00E+04 mg/L 25 EXP
Vapor Pressure 93.2 mm Hg 25 EXP
Henry's Law Constant 1.34E-04 atm-m3/mole 25 EXP
Atmospheric OH Rate Constant 1.60E-12 cm3/molecule-sec 25 EXP

Physical property data is provided to ChemIDplus by SRC, Inc.