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Substance Name: Mometasone furoate monohydrate
RN: 141646-00-6
UNII: MTW0WEG809
InChIKey: AQCCVUHZMIMSIB-HRVPQZBTSA-N
Note
- NCI: Mometasone furoate. The furoate salt form of mometasone, a synthetic topical glucocorticosteroid receptor agonist with anti-inflammatory, anti-pruritic and vasoconstrictive properties. Mometasone furoate exerts its effect by binding to cytoplasmic glucocorticoid receptors and subsequently activates glucocorticoid receptor mediated gene expression. This results in synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators.. Specifically, mometasone furoate appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from phospholipid membrane by phospholipase A2. (NCI Thesaurus)
Molecular Formula
- C27-H30-Cl2-O6.H2-O
Molecular Weight
- 539.4488
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Names and Synonyms
Name of Substance
- Mometasone furoate monohydrate
Synonyms
- Mometasone furoate hydrate
- Mometasone furoate monohydrate
- UNII-MTW0WEG809
Systematic Name
- Pregna-1,4-diene-3,20-dione, 9,21-dichloro-17-((2-furanylcarbonyl)oxy)-11-hydroxy-16-methyl-, monohydrate, (11beta,16alpha)-
Registry Numbers
CAS Registry Number
- 141646-00-6
FDA UNII
- MTW0WEG809
System Generated Number
- 0141646006
Molecular Formulas
Molecular Formula
- C27-H30-Cl2-O6.H2-O
Molecular Formula Fragments
- C27-H30-Cl2-O6
- COMPONENT
- H2-O