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Substance Name: Chlordecone [ISO]
RN: 143-50-0
UNII: RG5XJ88UDF
InChIKey: LHHGDZSESBACKH-UHFFFAOYSA-N

Note

  • A highly chlorinated polycyclic hydrocarbon insecticide whose large number of chlorine atoms makes it resistant to degradation. It has been shown to be toxic to mammals and causes abnormal cellular changes in laboratory animals.

Molecular Formula

  • C10-Cl10-O

Molecular Weight

  • 490.639
 

Classification Codes

Classification Codes

  • Agricultural Chemical
  • Fungicide, Bactericide, Wood Preservative
  • Insect Attractant, Repellent and Chemosterilant
  • Insecticide
  • Insecticides
  • Mutation Data
  • Out-Dated Pesticide
  • Pesticides
  • Reproductive Effect
  • Tumor Data

Superlist Classification Codes

  • 2007 CERCLA Priority List, Rank: 138
  • 2011 CERCLA Priority List, Rank: 135
  • Overall Carcinogenic Evaluation: Group 2B
  • Reasonably Anticipated to be a Carcinogen
  • Reportable Quantity (RQ) = 1 lb

Names and Synonyms

Results Name

  • Chlordecone [ISO]

Name of Substance

  • Chlordecone
  • Chlordecone [ISO]

MeSH Heading

  • Chlordecone

Synonyms

  • 1,1a,3,3a,4,5,5,5a,5b,6-Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta(cd)pentalen-2-one
  • 1,2,3,4,5,5,6,7,8,9,10,10-Dodecachlorooctahydro-1,3,4-metheno-2-cyclobuta(c,d)pentalone
  • 1,2,3,5,6,7,8,9,10,10-Decachloro(5.2.1.0(sup 2,6).0(sup 3,9).0(sup 5,8))decano-4-one
  • 1,3,4-Metheno-2H-cyclobuta(cd)pentalen-2-one, 1,1a,3,3a,4,5,5,5a,5b,6-decachlorooctahydro-
  • 2,3,3a,4,5,6,7,7a,8,8a-Decachloro-3a,4,7,7a-tetrahydro-4,7-methanoinden-1-one
  • AI3-16391
  • Caswell No. 275
  • CCRIS 128
  • Chlordecone
  • Ciba 8514
  • Clordecone
  • Compound 1189
  • Decachloro-1,3,4-metheno-2H-cyclobuta(cd)pentalen-2-one
  • Decachloroketone
  • Decachlorooctahydro-1,3,4-methano-2H-cyclobuta(cd)pentalen-2-one
  • Decachlorooctahydro-1,3,4-metheno-2H-cyclobuta(cd)pentalen-2-one
  • Decachloropentacyclo(5.2.1.0(2,6).0(3,9).0(5),(8))decan-4-one
  • Decachloropentacyclo(5.2.1.0(sup 2,6).0(sup 3,9).0(sup 5,8))decan-4-one
  • Decachloropentacyclo(5.3.0.0(sup 2,6).0(sup 4,10).0(sup 5,9))decan-3-one
  • Decachlorotetracyclodecanone
  • Decachlorotetrahydro-4,7-methanoindeneone
  • EINECS 205-601-3
  • ENT 16,391
  • EPA Pesticide Chemical Code 027701
  • GC 1189
  • General chemicals 1189
  • HSDB 1558
  • Kepone
  • Kepone-2-one, decachlorooctahydro-
  • Merex
  • NCI-C00191
  • NSC 124074
  • Perchloropentacyclo(5.3.0.0(2,6).0(3,9).0(4,8))decan-5-one
  • RCRA waste number U142
  • UNII-RG5XJ88UDF

Systematic Names

  • 1,3,4-Metheno-2H-cyclobuta(cd)pentalen-2-one, 1,1a,3,3a,4,5,5,5a,5b,6-decachlorooctahydro-
  • Chlordecone

Superlist Names

  • 1,3,4-Metheno-2H-cyclobuta(cd)pentalen-2-one, 1,1a,3,3a,4,5,5,5a,5b,6-decachlorooctahydro-
  • Chlordecone
  • Kepone
  • RCRA waste no. U142

Registry Numbers

CAS Registry Number

  • 143-50-0

FDA UNII

  • RG5XJ88UDF

System Generated Number

  • 0000143500

Structure Descriptors

InChI

1S/C10Cl10O/c11-2-1(21)3(12)6(15)4(2,13)8(17)5(2,14)7(3,16)9(6,18)10(8,19)20

InChIKey

LHHGDZSESBACKH-UHFFFAOYSA-N

Smiles

C12([C@@]3([C@@]4(C([C@@]5(Cl)C4(Cl)C(C3(Cl)[C@@]15Cl)=O)(Cl)C2(Cl)Cl)Cl)Cl)Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 250mg/kg (250mg/kg) BEHAVIORAL: TREMOR Toxicology and Applied Pharmacology. Vol. 45, Pg. 331, 1978.
mammal (species unspecified) LD50 unreported 126mg/kg (126mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 65, 1971.
quail LD50 oral 237mg/kg (237mg/kg)   Journal of Reproduction and Fertility. Vol. 48, Pg. 371, 1976.
rabbit LD50 oral 65mg/kg (65mg/kg)   Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 642, 1966.
rabbit LD50 skin 345mg/kg (345mg/kg)   Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 96, 1973.
rat LD50 oral 91300ug/kg (91.3mg/kg)   Neurobehavioral Toxicology and Teratology. Vol. 5, Pg. 91, 1983.
rat LD50 skin > 2gm/kg (2000mg/kg)   Toxicology and Applied Pharmacology. Vol. 14, Pg. 515, 1969.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 350 dec deg C   EXP
log P (octanol-water) 5.41 (none)   EXP
Water Solubility 2.7 mg/L 25 EXP
Vapor Pressure 2.25E-07 mm Hg 25 EXP
Henry's Law Constant 5.38E-08 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 0.0 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.