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Substance Name: Butabarbital sodium [USP]
RN: 143-81-7
UNII: 9WTD50I918
InChIKey: QORQZMBCPRBCAB-UHFFFAOYSA-M
Molecular Formula
- C10-H16-N2-O3.Na
Molecular Weight
- 234.2295
- All
- Classifications
- Links to Resources
- Names & Synonyms
- Registry Numbers
- Formulas
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
Classification Codes
- Drug / Therapeutic Agent
- Human Data
- Sedative-Hypnotic
Superlist Classification Code
- DEA Schedule III
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Names and Synonyms
Name of Substance
- Butabarbital sodium [USP]
Synonyms
- 5-Ethyl-5-(1-methylpropyl)barbituric acid sodium salt
- 5-sec-Butyl-5-ethylbarbituric acid sodium salt
- Asturidon
- Barbitab
- Bubartal
- Bubartal TT
- Butabarb
- Butabarbital
- Butabarbital sodium
- Butabarbitone sodium
- Butabarpal sodium
- Butak
- Butalan
- Butasaron
- Butased
- Butatal sodium
- Butazem
- Buticaps
- Butisol sodium
- Cambrised
- Carrbutabarb
- Ciprial
- DEA No. 2100
- EINECS 205-611-8
- Expansatol
- Insolat
- Intasedol
- Loubarb
- Mebutal
- Neravan
- Noctinal
- NSC 11778
- Paxital
- Paxital (VAN)
- Prelital
- Quiebar
- Sarisol
- Sarisol No. 1
- Sarisol No. 2
- Secbubarbital sodium
- Secbutabarbital sodique
- Secbutabarbital sodium
- Secbutobarbitone sodium
- Seda-Bute
- Sodium 5-ethyl-5-(1-methylpropyl)barbiturate
- Sodium 5-ethyl-5-sec-butylbarbiturate
- Sodium 5-sec-butyl-5-ethylbarbiturate
- Sodium butabarbital
- Sodium butobarbitone
- UNII-9WTD50I918
Systematic Names
- 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylpropyl)-, monosodium salt
- Barbituric acid, 5-sec-butyl-5-ethyl-, sodium salt
- Sodium 5-(sec-butyl)-5-ethylbarbiturate
Superlist Names
- Butabarbital sodium
- Butibel
- DEA No. 2100
Mixture Name
- Butibel
Registry Numbers
CAS Registry Number
- 143-81-7
FDA UNII
- 9WTD50I918
System Generated Number
- 0000143817
Molecular Formulas
Molecular Formula
- C10-H16-N2-O3.Na
Molecular Formula Fragments
- C10-H16-N2-O3
- COMPONENT
- Na
Structure Descriptors
InChI
1S/C10H16N2O3.Na/c1-4-6(3)10(5-2)7(13)11-9(15)12-8(10)14;/h6H,4-5H2,1-3H3,(H2,11,12,13,14,15);/q;+1/p-1InChIKey
QORQZMBCPRBCAB-UHFFFAOYSA-MSmiles
C1([C@@](C(N=C(N1)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | intravenous | 90mg/kg (90mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 81, Pg. 254, 1944. |
human | LDLo | oral | 125mg/kg (125mg/kg) | LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA | Clinical Toxicology. Vol. 10, Pg. 327, 1977. |
human | TDLo | oral | 120mg/kg (120mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: ANOREXIA (HUMAN BEHAVIORAL: ATAXIA | British Medical Journal. Vol. 1, Pg. 144, 1977. |
mouse | LD50 | intraperitoneal | 247mg/kg (247mg/kg) | VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 81, Pg. 254, 1944. |
rabbit | LD50 | intraperitoneal | 95mg/kg (95mg/kg) | VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 81, Pg. 254, 1944. |
rabbit | LD50 | intravenous | 91mg/kg (91mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Journal of Pharmacology and Experimental Therapeutics. Vol. 81, Pg. 254, 1944. |
rabbit | LD50 | oral | 194mg/kg (194mg/kg) | VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 81, Pg. 254, 1944. |
rat | LD50 | intraperitoneal | 70mg/kg (70mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION | Journal of Pharmacology and Experimental Therapeutics. Vol. 81, Pg. 254, 1944. |
rat | LD50 | intravenous | 70mg/kg (70mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 81, Pg. 254, 1944. |
rat | LD50 | oral | 78mg/kg (78mg/kg) | LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Journal of Pharmacology and Experimental Therapeutics. Vol. 81, Pg. 254, 1944. |
Physical Properties
Physical Property | Value | Units | Temp (deg C) | Source |
---|---|---|---|---|
log P (octanol-water) | -2.110 | (none) | EST | |
Water Solubility | 3.33E+05 | mg/L | EXP | |
Atmospheric OH Rate Constant | 2.01E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.