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Substance Name: Dextrophan tartrate
RN: 143-98-6
UNII: NFM769433K
InChIKey: RWTWIZDKEIWLKQ-XCPWPWHNSA-N
Classification Code
- Drug / Therapeutic Agent
Molecular Formula
- C17-H23-N-O.C4-H6-O6
Molecular Weight
- 407.46
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Names and Synonyms
Results Name
- Dextrophan tartrate
Name of Substance
- Dextrorphan tartrate
Synonyms
- 1,3,4,9,10,10a-Hexahydro-11-methyl-2H-10,4a-iminoethanophenanthren-6-ol tartrate, d-
- d-3-Hydroxy-N-methylmorphinan tartrate
- Dextrophan tartrate
- Dextrorphan tartrate
- Ro 1-6794
- UNII-NFM769433K
Systematic Name
- Morphinan-3-ol, 17-methyl-, tartrate (1:1) (salt), (+)-
Registry Numbers
CAS Registry Number
- 143-98-6
FDA UNII
- NFM769433K
System Generated Number
- 0000143986
Molecular Formulas
Molecular Formula
- C17-H23-N-O.C4-H6-O6
Molecular Formula Fragments
- C17-H23-N-O
- C4-H6-O6
- COMPONENT
Structure Descriptors
InChI
1S/C17H23NO.C4H6O6/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17;5-1(3(7)8)2(6)4(9)10/h5-6,11,14,16,19H,2-4,7-10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t14-,16+,17+;1-,2-/m11/s1InChIKey
RWTWIZDKEIWLKQ-XCPWPWHNSA-NSmiles
c12[C@]34CCCC[C@@H]3[C@@H]([N@](C)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intravenous | 42mg/kg (42mg/kg) | "Synthetic Analgesics," Oxford, Pergamon Press, 1966Vol. 2, Pg. 77, 1966. | |
mouse | LD50 | oral | 385mg/kg (385mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 109, Pg. 189, 1953. | |
mouse | LD50 | parenteral | 17414ug/kg (17.414mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 145, Pg. 11, 1964. | |
mouse | LD50 | subcutaneous | 350mg/kg (350mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 109, Pg. 189, 1953. | |
rabbit | LD50 | intravenous | 27500ug/kg (27.5mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: REGIDITY | Journal of Pharmacology and Experimental Therapeutics. Vol. 109, Pg. 189, 1953. |
rat | LD50 | oral | 1100mg/kg (1100mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 109, Pg. 189, 1953. | |
rat | LD50 | subcutaneous | 800mg/kg (800mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 109, Pg. 189, 1953. |