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Substance Name: Anakinra [USAN:INN:BAN]
RN: 143090-92-0
UNII: 9013DUQ28K
Note
- A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA.
Molecular Formula
- C759-H1186-N208-O232-S10
Molecular Weight
- 17257.6024
Classification Codes
- Anti-Inflammatory (Nonsteroidal)
- Antiarthritic
- Antirheumatic Agents
- Suppressant (Inflammatory Bowel Disease)
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Links to Resources
NLM Resources (File Locators)
Other Resources (Internet Locators)
Names and Synonyms
Name of Substance
- Anakinra [USAN:INN:BAN]
MeSH Heading
- Interleukin 1 Receptor Antagonist Protein
Synonyms
- Anakinra
- Antril
- IL-1RA
- Kineret
- N(sup 2)-L-Methionylinterleukin 1 receptor antagonist (human isoform x reduced)
- UNII-9013DUQ28K
Systematic Name
- Interleukin 1 receptor antagonist (human isoform x reduced), N(sup 2)-L-methionyl-
Registry Numbers
CAS Registry Number
- 143090-92-0
FDA UNII
- 9013DUQ28K
System Generated Number
- 0143090920