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Substance Name: Anakinra [USAN:INN:BAN]
RN: 143090-92-0
UNII: 9013DUQ28K


  • A ligand that binds to but fails to activate the INTERLEUKIN 1 RECEPTOR. It plays an inhibitory role in the regulation of INFLAMMATION and FEVER. Several isoforms of the protein exist due to multiple ALTERNATIVE SPLICING of its mRNA.

Molecular Formula

  • C759-H1186-N208-O232-S10

Molecular Weight

  • 17257.6024

Classification Codes

  • Anti-Inflammatory (Nonsteroidal)
  • Antiarthritic
  • Antirheumatic Agents
  • Suppressant (Inflammatory Bowel Disease)

Names and Synonyms

Name of Substance

  • Anakinra [USAN:INN:BAN]

MeSH Heading

  • Interleukin 1 Receptor Antagonist Protein


  • Anakinra
  • Antril
  • IL-1RA
  • Kineret
  • N(sup 2)-L-Methionylinterleukin 1 receptor antagonist (human isoform x reduced)
  • UNII-9013DUQ28K

Systematic Name

  • Interleukin 1 receptor antagonist (human isoform x reduced), N(sup 2)-L-methionyl-

Registry Numbers

CAS Registry Number

  • 143090-92-0


  • 9013DUQ28K

System Generated Number

  • 0143090920