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Substance Name: L 685818
RN: 143839-74-1
InChIKey: NOQNPBXNHMZMTC-VFJJZZNKSA-N
Note
- The C18-hydroxy, C21-ethyl analog of FK-506; binds to FKBP-12; antagonizes FK-506 and rapamycin.
Molecular Formula
- C43-H69-N-O13
Molecular Weight
- 808.0121
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Names and Synonyms
Name of Substance
- L 685818
Synonyms
- L 685,818
- L-685,818
- L-685818
Systematic Names
- 15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,11,19-trihydroxy-3-((1E)-2-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-, (3S,4R,5S,8R,9E,11S,12R,14S,15R,16S,18R,19R,26aS)-
- 15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,11,19-trihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-, (3S-(3R*(E(1S*,3S*,4S*)),4S*,5R*,8S*,9E,11R*,12S*,14R*,15S*,16R*,18S*,19S*,26aR*))-
Registry Numbers
CAS Registry Number
- 143839-74-1
System Generated Number
- 0143839741