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Substance Name: Piperazine Citrate
RN: 144-29-6
UNII: RI85381D5G
InChIKey: JDDHUROHDHPVIO-UHFFFAOYSA-N

Classification Codes

  • Anthelmintics
  • Anti-Infective Agents
  • Antiparasitic Agents
  • Drug / Therapeutic Agent
  • Human Data

Molecular Formula

  • C6-H8-O7.3/2C4-H10-N2

Molecular Weight

  • 642.6554
 
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Names and Synonyms

Results Name

  • Piperazine citrate

Name of Substance

  • Piperazine citrate
  • Piperazine citrate anhydrous

Synonyms

  • AI3-27243
  • Antepar
  • Anthecole
  • Antoban
  • Arpezine
  • Arpezine (VAN)
  • Ascarex Syrup
  • Bryrel
  • DAK 63
  • EINECS 205-622-8
  • Exelmin
  • Exopin
  • Helmezine
  • Helmizin
  • Multifuge
  • Multifuge citrate
  • Nemadital
  • NSC 86779
  • Oxucide
  • Oxyzin
  • Oxyzin (syrup) (VAN)
  • Oxyzine
  • Oxyzine (syrup)
  • Parazine
  • Parazine citrate
  • Pin-Tega
  • Pinozan
  • Piperasol
  • Piperazine citrate
  • Piperazine Citrate Telra
  • Piperazine Citrate USP
  • Pipizan
  • Pipizan Citrate Syrup
  • Pro pet
  • Rhomex
  • Ta-Verm
  • Tasnon
  • Tripiperazine dicitrate
  • UNII-RI85381D5G
  • Vermago
  • Vermidol
  • Vermizine (elixir)

Systematic Names

  • Piperazine, 2-hydroxy-1,2,3-propanetricarboxylate (3:2)
  • Piperazine, citrate (3:2)
  • Tripiperazine dicitrate

Registry Numbers

CAS Registry Number

  • 144-29-6

FDA UNII

  • RI85381D5G

Other Registry Number

  • 113484-97-2

Related Registry Number

  • 41372-10-5 (unspecified hydrate)

System Generated Number

  • 0000144296

Molecular Formulas

Molecular Formula

  • C6-H8-O7.3/2C4-H10-N2

Molecular Formula Fragments

  • C4-H10-N2
  • C6-H8-O7
  • COMPONENT

Structure Descriptors

InChI

1S/2C6H8O7.3C4H10N2/c2*7-3(8)1-6(13,5(11)12)2-4(9)10;3*1-2-6-4-3-5-1/h2*13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);3*5-6H,1-4H2

InChIKey

JDDHUROHDHPVIO-UHFFFAOYSA-N

Smiles

OC(=O)CC(O)(CC(=O)O)C(=O)O.OC(=O)CC(O)(CC(=O)O)C(=O)O.C1CNCCN1.C2CNCCN2.C3CNCCN3

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
child LDLo oral 260mg/kg/3D-I (260mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

BEHAVIORAL: COMA

BEHAVIORAL: HEADACHE
Lancet. Vol. 1, Pg. 895, 1967.
infant TDLo unreported 500mg/kg/2D (500mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: COMA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Indian Pediatrics. Vol. 18, Pg. 71, 1981.
man TDLo oral 150mg/kg/5D (150mg/kg) GASTROINTESTINAL: NAUSEA OR VOMITING

BEHAVIORAL: TREMOR

SENSE ORGANS AND SPECIAL SENSES: DIPLOPIA: EYE
JAMA, Journal of the American Medical Association. Vol. 161, Pg. 515, 1956.
mouse LD50 intraperitoneal 3548mg/kg (3548mg/kg) SKIN AND APPENDAGES (SKIN): SWEATING: OTHER

BEHAVIORAL: EXCITEMENT
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 274, Pg. 253, 1985.
mouse LD50 oral 8500mg/kg (8500mg/kg) BEHAVIORAL: ATAXIA

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of Medicinal Chemistry. Vol. 6, Pg. 336, 1963.
mouse LDLo intravenous 100mg/kg (100mg/kg)   Compilation of LD50 Values of New Drugs.
rabbit LDLo intravenous 175mg/kg (175mg/kg)   Compilation of LD50 Values of New Drugs.
rat LD50 oral 11200mg/kg (11200mg/kg) BEHAVIORAL: ATAXIA

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Journal of Medicinal Chemistry. Vol. 6, Pg. 336, 1963.