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Substance Name: Febuxostat [USAN:INN:BAN]
RN: 144060-53-7
UNII: 101V0R1N2E
InChIKey: BQSJTQLCZDPROO-UHFFFAOYSA-N

Note

  • A thiazole derivative and inhibitor of XANTHINE OXIDASE that is used for the treatment of HYPERURICEMIA in patients with chronic GOUT.

Molecular Formula

  • C16-H16-N2-O3-S

Molecular Weight

  • 316.3794
 

Classification Codes

  • Antirheumatic Agents
  • Gout Suppressants
  • Management of Hyperuricemia in Patients with Gout (Xanthine Oxidase/Xanthine Dehydrogenase Inhibitor)

Names and Synonyms

Name of Substance

  • Febuxostat
  • Febuxostat [USAN:INN:BAN]

MeSH Heading

  • Febuxostat

Synonyms

  • 2-(3-Cyano-4-(2-methylpropoxy)phenyl)-4-methylthiazole-5-carboxylic acid
  • 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylic acid
  • 5-Thiazolecarboxylic acid, 2-(3-cyano-4-(2-methylpropoxy)phenyl)-4-methyl-
  • Adenuric
  • Feburic
  • Febuxostat
  • NSC 758874
  • TEI 6720
  • Tei-6720
  • TMX 67
  • TMX-67
  • Uloric
  • UNII-101V0R1N2E
  • Zurig

Systematic Names

  • 2-(3-Cyano-4-(2-methylpropoxy)phenyl)-4-methylthiazole-5-carboxylic acid
  • 5-Thiazolecarboxylic acid, 2-(3-cyano-4-(2-methylpropoxy)phenyl)-4-methyl-

Registry Numbers

CAS Registry Number

  • 144060-53-7

FDA UNII

  • 101V0R1N2E

System Generated Number

  • 0144060537

Structure Descriptors

InChI

InChI=1S/C16H16N2O3S/c1-9(2)8-21-13-5-4-11(6-12(13)7-17)15-18-10(3)14(22-15)16(19)20/h4-6,9H,8H2,1-3H3,(H,19,20)

InChIKey

BQSJTQLCZDPROO-UHFFFAOYSA-N

Smiles

CC(C)COc1ccc(cc1C#N)c2nc(C)c(s2)C(=O)O