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Substance Name: Placenta growth factor
RN: 144321-81-3


  • An angiogenic protein belonging to the Vascular Endothelial Growth Factor family of growth factors originally isolated and cloned from human placental cDNA library. There are four isoforms of PLGF 1-4 which result from alternative splicing. Placenta Growth Factor is secreted as a glycosylated homodimer which acts as a mitogen for endothelial cells, and its expression is markedly upregulated during hypoxia and in tissue inflammation and cancer.
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Names and Synonyms

Name of Substance

  • Placenta growth factor

MeSH Heading

  • Placenta Growth Factor


  • Pifg (factor)
  • Placenta growth factor
  • Placental growth factor
  • Plgf protein

Systematic Name

  • Protein PIGF (human clone pPIGF-2118-amino acid isoform precursor reduced)

Registry Numbers

CAS Registry Number

  • 144321-81-3

Other Registry Number

  • 144589-93-5

System Generated Number

  • 0144321813