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Substance Name: Pancreatitis-associated protein
RN: 144416-83-1


  • C-type lectins that restrict growth of bacteria in the intestinal epithelia and have bactericidal activity against gram-positive and gram-negative bacteria. They also regulate proliferation and differentiation of KERATINOCYTES following injury. Human pancreatitis-associated protein-1 (Reg3a) is overexpressed by pancreatic ACINAR CELLS in patients with CHRONIC PANCREATITIS. It is also highly expressed by pancreatic, bladder, and gastrointestinal cancer cells and may serve as a diagnostic biomarker.
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Names and Synonyms

Name of Substance

  • Pancreatitis-associated protein

MeSH Heading

  • Pancreatitis-Associated Proteins


  • Hip gene product
  • Hip protein
  • Pancreatitis-associated protein I
  • Pancreatitis-associated protein II
  • Pancreatitis-associated protein III
  • PAP-H
  • Peptide 23
  • PTAP

Systematic Name

  • Protein PAP (rat clone 4R/10-3/10-5 pancreatitis associated-precursor reduced)

Registry Numbers

CAS Registry Number

  • 144416-83-1

System Generated Number

  • 0144416831