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Substance Name: Bumadizon sodium
RN: 14467-30-2
UNII: PP47GRI92P
InChIKey: JSKMFBFCHQMLJR-UHFFFAOYSA-M

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C19-H21-N2-O3.Na

Molecular Weight

  • 348.376
 
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Names and Synonyms

Results Name

  • Bumadizon sodium

Name of Substance

  • Bumadizone sodium

Synonyms

  • B-64114 Na
  • Bumadizon natrium
  • Bumadizon natrium [German]
  • Bumadizon sodium
  • Butyl-malonsaeure-mono-(1,2-diphenyl-hydrazid)-natrium
  • Butyl-malonsaeure-mono-(1,2-diphenyl-hydrazid)-natrium [German]
  • Butylpropanedioic acid mono(1,2-diphenylhydrazide) monosodium salt
  • Malonic acid, butyl-, mono(1,2-diphenylhydrazide), monosodium salt
  • UNII-PP47GRI92P

Systematic Name

  • Propanedioic acid, butyl-, mono(1,2-diphenylhydrazide), monosodium salt

Registry Numbers

CAS Registry Number

  • 14467-30-2

FDA UNII

  • PP47GRI92P

System Generated Number

  • 0014467302

Molecular Formulas

Molecular Formula

  • C19-H21-N2-O3.Na

Molecular Formula Fragments

  • C19-H21-N2-O3
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C19H22N2O3.Na/c1-2-3-14-17(19(23)24)18(22)21(16-12-8-5-9-13-16)20-15-10-6-4-7-11-15;/h4-13,17,20H,2-3,14H2,1H3,(H,23,24);/q;+1/p-1

InChIKey

JSKMFBFCHQMLJR-UHFFFAOYSA-M

Smiles

N(c1ccccc1)(C([C@@H](CCCC)C(=O)[O-])=O)Nc1ccccc1.[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 420mg/kg (420mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 67, Pg. 337, 1971.
mouse LD50 oral 1400mg/kg (1400mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 67, Pg. 337, 1971.
rabbit LD50 intravenous 240mg/kg (240mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 67, Pg. 337, 1971.