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Substance Name: Dihydroprogesterone
RN: 145-14-2
UNII: 45630A64AC
InChIKey: RWBRUCCWZPSBFC-RXRZZTMXSA-N

Note

  • A biologically active 20-alpha-reduced metabolite of PROGESTERONE. It is converted from progesterone to 20-alpha-hydroxypregn-4-en-3-one by the 20-ALPHA-HYDROXYSTEROID DEHYDROGENASE in the CORPUS LUTEUM and the PLACENTA.

Molecular Formula

  • C21-H32-O2

Molecular Weight

  • 316.482
 

Classification Codes

  • Hormone
  • Hormones
  • Hormones, Hormone Substitutes, and Hormone Antagonists
  • Mutation Data
  • Progestins
  • Reproductive Effect
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Names and Synonyms

Name of Substance

  • Dihydroprogesterone

MeSH Heading

  • 20-alpha-Dihydroprogesterone

Synonyms

  • (20S)-20-Hydroxypregn-4-en-3-one
  • 20(S)-Hydroxyprogesterone
  • 20-alpha-Dihydroprogesterone
  • 20-alpha-Hydroxydihydroprogesterone
  • 20-alpha-Hydroxyprogesterone
  • 20-alpha-Progerol
  • 20alpha-Dihydroprogesterone
  • 20alpha-Dihydroprognenolone
  • 20alpha-Hydroxydihydroprogesterone
  • 20alpha-Hydroxypreg-4-en-3-one
  • 20alpha-Hydroxypregnen-2-one
  • 20alpha-Progerol
  • 4-08-00-01018 (Beilstein Handbook Reference)
  • BRN 2220567
  • Dihydrogesterone
  • Dihydroprogesterone
  • EINECS 205-649-5
  • NSC 68630
  • Progesterol-20-alpha
  • UNII-45630A64AC

Systematic Names

  • (20S)-20-Hydroxypregn-4-en-3-one
  • Pregn-4-en-3-one, 20-alpha-hydroxy-
  • Pregn-4-en-3-one, 20-hydroxy-, (20S)- (9CI)
  • Pregn-4-en-3-one, 20alpha-hydroxy- (8CI)

Registry Numbers

CAS Registry Number

  • 145-14-2

FDA UNII

  • 45630A64AC

System Generated Number

  • 0000145142

Structure Descriptors

InChI

1S/C21H32O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12-13,16-19,22H,4-11H2,1-3H3/t13-,16-,17+,18-,19-,20-,21+/m0/s1

InChIKey

RWBRUCCWZPSBFC-RXRZZTMXSA-N

Smiles

C1[C@H]2[C@H]([C@H]3[C@@]([C@@H]([C@H](C)O)CC3)(C)C1)CCC=1[C@@]2(CCC(C1)=O)C