Skip Navigation
ChemIDplus A TOXNET DATABASE Lite•Browse•Advanced

Substance Name: Tritoqualine [INN:DCF]
RN: 14504-73-5
UNII: F4MW5166YH
InChIKey: IRGJVQIJENCTQF-UHFFFAOYSA-N

Classification Codes

  • Drug / Therapeutic Agent
  • Histamine Agents
  • Histamine Antagonists
  • Histamine H1 Antagonists
  • Neurotransmitter Agents

Molecular Formula

  • C26-H32-N2-O8

Molecular Weight

  • 500.5448
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Tritoqualine
  • Tritoqualine [INN:DCF]

Synonyms

  • 35NZ
  • 4,5,6-Triethoxy-7-amino-3-(8-methoxy-2-methyl-6,7-methylenedioxy-1,2,3,4-tetrahydro-1-isochinolinyl)phthalid
  • 554L
  • 7-Amino-4,5,6-triethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)phthalide
  • BRN 0634993
  • Hypostamin
  • Hypostamine
  • Inhibostamin
  • L 554
  • L-554
  • MCI-5011
  • Tritocualina
  • Tritocualina [INN-Spanish]
  • Tritocualina [Spanish]
  • Tritoqualine
  • Tritoqualinum
  • Tritoqualinum [INN-Latin]
  • UNII-F4MW5166YH

Systematic Names

  • 1(3H)-Isobenzofuranone, 7-amino-4,5,6-triethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-
  • 7-Amino-4,5,6-triethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-1(3H)-isobenzofuranone
  • 7-Amino-4,5,6-triethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)phthalide

Registry Numbers

CAS Registry Number

  • 14504-73-5

FDA UNII

  • F4MW5166YH

Other Registry Numbers

  • 20438-00-0
  • 4835-67-0
  • 6429-02-3

System Generated Number

  • 0014504735

Structure Descriptors

InChI

1S/C26H32N2O8/c1-6-31-23-17-16(18(27)24(32-7-2)25(23)33-8-3)26(29)36-21(17)19-15-13(9-10-28(19)4)11-14-20(22(15)30-5)35-12-34-14/h11,19,21H,6-10,12,27H2,1-5H3

InChIKey

IRGJVQIJENCTQF-UHFFFAOYSA-N

Smiles

CCOc1c2c(c(c(c1OCC)OCC)N)C(=O)OC2C3c4c(cc5c(c4OC)OCO5)CCN3C

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 15gm/kg (15000mg/kg) GASTROINTESTINAL: DECREASED MOTILITY OR CONSTIPATION

SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

SKIN AND APPENDAGES (SKIN): HAIR: OTHER		 Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 1129, 1986.
mouse LD50 oral > 15gm/kg (15000mg/kg) KIDNEY, URETER, AND BLADDER: OTHER CHANGES

AUTONOMIC NERVOUS SYSTEM: "SMOOTH MUSCLE RELAXANT (MECHANISM UNDEFINED, SPASMOLYTIC)"		 Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 1129, 1986.
mouse LD50 subcutaneous > 15gm/kg (15000mg/kg) BLOOD: CHANGES IN SPLEEN

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"		 Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 1129, 1986.
rat LD50 intraperitoneal > 15gm/kg (15000mg/kg) GASTROINTESTINAL: DECREASED MOTILITY OR CONSTIPATION

SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE

SKIN AND APPENDAGES (SKIN): HAIR: OTHER		 Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 1129, 1986.
rat LD50 oral > 15gm/kg (15000mg/kg) KIDNEY, URETER, AND BLADDER: OTHER CHANGES

AUTONOMIC NERVOUS SYSTEM: "SMOOTH MUSCLE RELAXANT (MECHANISM UNDEFINED, SPASMOLYTIC)"		 Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 1129, 1986.
rat LD50 subcutaneous > 15gm/kg (15000mg/kg) BLOOD: CHANGES IN SPLEEN

SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"		 Oyo Yakuri. Pharmacometrics. Vol. 31, Pg. 129, 1986.