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Substance Name: Tegaserod [USAN:INN:BAN]
RN: 145158-71-0
UNII: 458VC51857
InChIKey: IKBKZGMPCYNSLU-UHFFFAOYSA-N

Note

  • A nonbenzamide 5-hydroxytryptamine(4) agonist; used in treatment of irritable bowel syndrome; marketing suspended 2007 in US due to higher incidence of MI, stroke, and unstable angina.

Molecular Formula

  • C16-H23-N5-O

Molecular Weight

  • 301.3917
 

Classification Codes

  • Gastrointestinal Agents
  • Neurotransmitter Agents
  • Serotonin Agents
  • Serotonin Agonists
  • Serotonin Receptor Agonists
  • Treatment of Gastrointestinal Motility Disorders
  • Treatment of Gastrointestinal Motility Disorders (Selective Serotonin 5HT4 Antagonist)

Names and Synonyms

Name of Substance

  • Tegaserod
  • Tegaserod [USAN:INN:BAN]

Synonyms

  • 1-(((5-Methoxyindol-3-yl)methylene)amino)-3-pentylguanidine
  • HTF 919
  • Hydrazinecarboximidamide, 2-((5-methoxy-1H-indol-3-yl)methylene)-N-pentyl-
  • SDZ HTF 919
  • SDZ-HTF-919
  • Tegaserod
  • UNII-458VC51857
  • Zelmac
  • Zelnorm

Systematic Name

  • Hydrazinecarboximidamide, 2-((5-methoxy-1H-indol-3-yl)methylene)-N-pentyl-

Registry Numbers

CAS Registry Number

  • 145158-71-0

FDA UNII

  • 458VC51857

Related Registry Number

  • 189188-57-6 (maleate)

System Generated Number

  • 0145158710

Structure Descriptors

InChI

1S/C16H23N5O/c1-3-4-5-8-18-16(17)21-20-11-12-10-19-15-7-6-13(22-2)9-14(12)15/h6-7,9-11,19H,3-5,8H2,1-2H3,(H3,17,18,21)

InChIKey

IKBKZGMPCYNSLU-UHFFFAOYSA-N

Smiles

CCCCCNC(=N)NN=Cc1c[nH]c2c1cc(cc2)OC