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Substance Name: Acridine mustard
RN: 146-59-8
UNII: 0I3A3407T2
InChIKey: PWGOWIIEVDAYTC-UHFFFAOYSA-N

Classification Codes

  • Alkylating Agents
  • Antineoplastic Agents
  • Antineoplastic Agents, Alkylating
  • Mutagens
  • Mutation Data
  • Noxae
  • Reproductive Effect
  • Tumor Data

Molecular Formula

  • C21-H25-Cl2-N3-O.2Cl-H

Molecular Weight

  • 479.2763
 
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Names and Synonyms

Name of Substance

  • Acridine mustard

Synonyms

  • 1,3-Propanediamine, N-(2-chloroethyl)-N'-(6-chloro-2-methoxy-9-acridinyl)-N-ethyl-, 2HCl
  • 6-Chloro-9-(3-(ethyl-2-chloroethyl)aminopropylamino)-2-methoxyacridine dihydrochloride
  • 9-(3-(Ethyl(2-chloroethyl)amino)propylamino)-6-chloro-2-methoxyacridine dihydrochloride
  • Acridine mustard
  • CCRIS 1091
  • EINECS 205-675-7
  • ICR 170
  • ICR-170
  • UNII-0I3A3407T2

Systematic Names

  • 1,3-Propanediamine, N-(2-chloroethyl)-N'-(6-chloro-2-methoxy-9-acridinyl)-N-ethyl-, dihydrochloride
  • 6-Chloro-9-((3-((2-chloroethyl)ethylamino)propyl)amino)-2-methoxyacridine dihydrochloride
  • Acridine, 6-chloro-9-(3-(N-(2-chloroethyl)-N-ethylamino)propylamino)-2-methoxy-, dihydrochloride
  • ICR 170

Registry Numbers

CAS Registry Number

  • 146-59-8

FDA UNII

  • 0I3A3407T2

System Generated Number

  • 0000146598

Molecular Formulas

Molecular Formula

  • C21-H25-Cl2-N3-O.2Cl-H

Molecular Formula Fragments

  • C21-H25-Cl2-N3-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C21H25Cl2N3O.2ClH/c1-3-26(12-9-22)11-4-10-24-21-17-7-5-15(23)13-20(17)25-19-8-6-16(27-2)14-18(19)21;;/h5-8,13-14H,3-4,9-12H2,1-2H3,(H,24,25);2*1H

InChIKey

PWGOWIIEVDAYTC-UHFFFAOYSA-N

Smiles

CCN(CCCNc1c2ccc(cc2nc3c1cc(cc3)OC)Cl)CCCl.Cl.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD20 intraperitoneal 2mg/kg (2mg/kg)   Journal of Medicinal Chemistry. Vol. 15, Pg. 739, 1972.
mouse LDLo intravenous 5mg/kg (5mg/kg)   Cancer Research. Vol. 36, Pg. 2423, 1976.