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Substance Name: Selegiline [USAN:INN:BAN]
RN: 14611-51-9
UNII: 2K1V7GP655
InChIKey: MEZLKOACVSPNER-GFCCVEGCSA-N

Note

  • A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl.

Molecular Formula

  • C13-H17-N

Molecular Weight

  • 187.2843
 

Classification Codes

  • Anti-Dyskinesia Agents
  • Antidepressant (MAO Inhibitor)
  • Antiparkinson Agents
  • Central Nervous System Agents
  • Enzyme Inhibitors
  • Monoamine Oxidase Inhibitors
  • Neuroprotective Agents
  • Protective Agents

Names and Synonyms

Name of Substance

  • Selegiline
  • Selegiline [USAN:INN:BAN]

MeSH Heading

  • Selegiline

Synonyms

  • (-)-(N)-Methyl-N-((1R)-1-methyl-2-phenylethyl)prop-2-yn-1-amine
  • (-)-Deprenil
  • (-)-Selegiline
  • (R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine
  • (R)-(-)-N-Methyl-N-(1-phenyl-2-propyl)-2-propinylamin
  • (R)-(-)-Selegiline
  • Anipryl
  • Benzeneethanamine, N,alpha-methyl-N-2-propynyl-, (alphaR)-
  • Carbex
  • Eldepryl
  • Emsam
  • Jumex
  • L-Deprenalin
  • l-Deprenyl
  • l-E 250
  • Selegilina
  • Selegilina [INN-Spanish]
  • Selegiline
  • Selegilinum
  • Selegilinum [INN-Latin]
  • Selgene
  • UNII-2K1V7GP655
  • Zalapar

Systematic Name

  • Benzeneethanamine, N,alpha-dimethyl-N-2-propynyl-, (R)-

Registry Numbers

CAS Registry Number

  • 14611-51-9

FDA UNII

  • 2K1V7GP655

Other Registry Number

  • 172964-89-5

Related Registry Numbers

  • 14611-52-0 (hydrochloride)
  • 2079-54-1 (deprenyl.hydrochloride)

System Generated Number

  • 0014611519

Structure Descriptors

InChI

1S/C13H17N/c1-4-10-14(3)12(2)11-13-8-6-5-7-9-13/h1,5-9,12H,10-11H2,2-3H3/t12-/m1/s1

InChIKey

MEZLKOACVSPNER-GFCCVEGCSA-N

Smiles

C[C@H](Cc1ccccc1)N(C)CC#C