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Substance Name: Colchiceine, N-deacetyl-N-benzoyl-
RN: 14686-58-9
InChIKey: IHMBFORMNABTCS-IBGZPJMESA-N

Molecular Formula

  • C26-H25-N-O6

Molecular Weight

  • 447.4845
 
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Names and Synonyms

Synonyms

  • Benzo(a)heptalen-9(5H)-one, 7-benzamido-6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-
  • Colchiceine, N-benzoyl-N-deacetyl-
  • N-Benzoyl trimethylcolchicinic acid

Systematic Names

  • Benzamide, N-(5,6,7,9-terahydro-10-hydroxy-1,2,3-trimethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-
  • Colchiceine, N-deacetyl-N-benzoyl-

Registry Numbers

CAS Registry Number

  • 14686-58-9

System Generated Number

  • 0014686589

Structure Descriptors

InChI

1S/C26H25NO6/c1-31-22-13-16-9-11-19(27-26(30)15-7-5-4-6-8-15)18-14-21(29)20(28)12-10-17(18)23(16)25(33-3)24(22)32-2/h4-8,10,12-14,19H,9,11H2,1-3H3,(H,27,30)(H,28,29)/t19-/m0/s1

InChIKey

IHMBFORMNABTCS-IBGZPJMESA-N

Smiles

COc1cc2CC[C@H](NC(=O)c3ccccc3)C4=CC(=O)C(=CC=C4c2c(OC)c1OC)O

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal > 700mg/kg (700mg/kg) BEHAVIORAL: SLEEP

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Cancer Vol. 3, Pg. 124, 1950.