Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Guanine-nucleotide-releasing factor
RN: 147979-76-8

Notes

  • A 145-kDa guanine nucleotide exchange factor that is specific for rap1 and ras GTP-BINDING PROTEINS. It associates with SH3 domains of the crk family of signaling proteins.
  • A family of GUANINE NUCLEOTIDE EXCHANGE FACTORS that are specific for RAS PROTEINS.
  • A guanine nucleotide exchange factor that acts to restore EUKARYOTIC INITIATION FACTOR-2 to its GTP bound form.
  • A mammalian homolog of the DROSOPHILA SON OF SEVENLESS PROTEIN. It is a guanine nucleotide exchange factor for RAS PROTEINS.
 
* denotes mobile formatted website

Links to Resources

NLM Resources (File Locators)

Other Resources (Internet Locators)

Names and Synonyms

Name of Substance

  • Guanine-nucleotide-releasing factor

MeSH Headings

  • Eukaryotic Initiation Factor-2B
  • Guanine Nucleotide-Releasing Factor 2
  • ras Guanine Nucleotide Exchange Factors
  • Rho Guanine Nucleotide Exchange Factors
  • SOS1 Protein

Synonyms

  • 200-Kda guanine nucleotide-exhange protein
  • C3G Protein
  • co-Eif-2
  • co-Eif-2A
  • co-Eif-2B
  • co-Eif-2C
  • Eif-2 stimulating protein
  • Eif-2C
  • eIF2B
  • Eif2C protein
  • Eukaryotic initiation factor 2 stimulating protein
  • Gdp exchange factor
  • Gdp-GTP reversing factor
  • Gep p200
  • Grf protein
  • Grf1 protein, mammalian
  • Grf2 protein, mammalian
  • Guanine nucleotide exchange factor
  • Guanine nucleotide releasing protein
  • Guanine nucleotide-releasing factor H-grf55
  • Guanosine nucleotide exchange factor
  • Mammalian sos1 protein
  • Mammalian sos2 protein
  • Msos protein
  • Msos1 protein
  • Msos2 protein
  • Ost protein
  • p115 Rhogef
  • p115RhoGEF
  • p200 Gep
  • Protein factor RF
  • Ras guanine nucleotide exchange factor
  • Ras nucleotide exchange factor
  • Ras-grf
  • Ras-grf2
  • Reversing factor gdp-GTP
  • Rhogef

Systematic Name

  • Protein Ras-GRF (rat guanine nucleotide-releasing reduced)

Registry Numbers

CAS Registry Number

  • 147979-76-8

System Generated Number

  • 0147979768