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Substance Name: Doripenem [USAN:INN]
RN: 148016-81-3
UNII: BHV525JOBH
InChIKey: AVAACINZEOAHHE-VFZPANTDSA-N
Note
- A carbapenem derivative antibacterial agent that is more stable to renal dehydropeptidase I than IMIPENEM, but does not need to be given with an enzyme inhibitor such as CILASTATIN. It is used in the treatment of infections such as HOSPITAL-ACQUIRED PNEUMONIA, and complicated intra-abdominal or urinary-tract infections, including PYELONEPHRITIS.
Molecular Formula
- C15-H24-N4-O6-S2
Molecular Weight
- 420.5086
Classification Codes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Antibacterial
- Antibiotic
- Carbapenem
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Names and Synonyms
Name of Substance
- Doripenem [USAN:INN]
MeSH Heading
- Doripenem
Synonyms
- (+)-(4R,5S,6S)-6-((1R)-1-Hydroxyethyl)-4-methyl-7-oxo-3-(((3S,5S)-5-((sulfamoylamino)methyl)-3-pyrrolidinyl)thio)-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid
- Doribax
- Doripenem
- Finibax
- S 4661
- S-4661
- UNII-BHV525JOBH
Systematic Names
- 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-(((3S,5S)-5-(((aminosulfonyl)amino)methyl)-3-pyrrolidinyl)thio)-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-, (4R,5S,6S)-
- 1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 3-((5-(((aminosulfonyl)amino)methyl)-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl-7-oxo-, (4R-(3(3S*,5S*),4alpha,5beta,6beta(R*)))-
- Doripenem
Registry Numbers
CAS Registry Number
- 148016-81-3
FDA UNII
- BHV525JOBH
System Generated Number
- 0148016813