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Substance Name: Vosoritide [USAN:INN]
RN: 1480724-61-5
UNII: 7SE5582Q2P
InChIKey: IGYWDDBBJPSOTG-WBAGYEQSSA-N
Notes
- A biologic analogue of C-type natriuretic peptide, a potent stimulator of endochondral ossification.
- WHO: a modified recombinant human C-type natriuretic peptide (CNP) consisting of 39 amino acids comprised of the 37 C-terminal amino acids of the human CNP sequence plus the addition of 2 amino acids (Pro-Gly) on the N-terminus, produced in Escherichia coli: L-prolylglycyl-(human C-type natriuretic peptide-(17-53)-peptide (CNP-37)), cyclic-(23-39)-disulfide. (WHO Drug Information)
Molecular Formula
- C176-H290-N56-O51-S3
Molecular Weight
- 4102.766
Classification Code
- Treatment of Acondroplasia
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Names and Synonyms
Name of Substance
- Vosoritide [USAN:INN]
Synonyms
- BMN 111
- BMN-111
- UNII-7SE5582Q2P
- Vosoritide
- Voxzogo
Systematic Name
- L-Cysteine, L-prolylglycyl-L-glutaminyl-L-.alpha.-glutamyl-L-histidyl-L-prolyl-L-asparaginyl-L-alanyl-L-arginyl-L-lysyl-L-tyrosyl-L-lysylglycyl-L-alanyl-L-asparaginyl-L-lysyl-L-lysylglycyl-L-leucyl-L-seryl-L-lysylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-leucyl-L-lysyl-L-leucyl-L-.alpha.-aspartyl-L-arginyl-L-isoleucylglycyl-L-seryl-L-methionyl-L-serylglycyl-L-leucylglycyl-, cyclic (23->39)-disulfide
Registry Numbers
CAS Registry Number
- 1480724-61-5
FDA UNII
- 7SE5582Q2P
System Generated Number
- 1480724615