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Substance Name: Ripisartan [INN]
RN: 148504-51-2
UNII: 7LQ7OQP653
InChIKey: OLJAPHMBAMBVKL-UHFFFAOYSA-N

Note

  • Angiotensin receptor antagonist.

Molecular Formula

  • C23-H22-N8-O

Molecular Weight

  • 426.4818
 
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Names and Synonyms

Results Name

  • Ripisartan [INN]

Name of Substance

  • Ripisartan [INN]
  • UP 269-6

Synonyms

  • 5-Methyl-7-n-propyl-8-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-(1,2,4)-triazolo(1,5-c)pyrimidin-2(3H)-one
  • 5-Methyl-7-propyl-8-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-(1,2,4)triazolo(1,5-c)pyrimidin-2(3H)-one
  • 5-Methyl-7-propyl-8-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-s-triazolo(1,5-c)pyrimidin-2(3H)-one
  • Ripisartan
  • UNII-7LQ7OQP653
  • UP-269-6

Systematic Name

  • (1,2,4)Triazolo(1,5-c)pyrimidin-2(3H)-one, 5-methyl-7-propyl-8-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-

Registry Numbers

CAS Registry Number

  • 148504-51-2

FDA UNII

  • 7LQ7OQP653

System Generated Number

  • 0148504512

Structure Descriptors

InChI

1S/C23H22N8O/c1-3-6-20-19(22-25-23(32)28-31(22)14(2)24-20)13-15-9-11-16(12-10-15)17-7-4-5-8-18(17)21-26-29-30-27-21/h4-5,7-12H,3,6,13H2,1-2H3,(H,28,32)(H,26,27,29,30)

InChIKey

OLJAPHMBAMBVKL-UHFFFAOYSA-N

Smiles

CCCc1c(c2nc(=O)[nH]n2c(n1)C)Cc3ccc(cc3)c4ccccc4c5[nH]nnn5

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
rat LD50 oral > 300mg/kg (300mg/kg)   United States Patent Document. Vol. #5217973,