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Substance Name: Bismuth subsalicylate [USAN:USP:JAN]
RN: 14882-18-9
UNII: 62TEY51RR1
InChIKey: ZREIPSZUJIFJNP-UHFFFAOYSA-K
Note
- Bismuth subsalicylate is the active ingredient of Pepto-Bismol and in Kaopectate; used to treat nausea, heartburn, indigestion, upset stomach, diarrhea and other temporary discomforts of the stomach; used with Azoles and other drugs to treat Helicobacter.
Molecular Formula
- C7-H5-Bi-O4
Molecular Weight
- 362.092
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- Classifications
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- Names & Synonyms
- Registry Numbers
- Structure Descriptors
- Toxicity
- Physical Properties
Classification Codes
- Agricultural Chemical
- Antacid
- Anti-Ulcerative
- Antidiarrheal
- Antidiarrheals
- Fungicide, Bactericide, Wood Preservative
- Gastrointestinal Agents
- Human Data
- TSCA Flag PMN (a Commenced PMN (Premanufacture Notice) Substance)
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Names and Synonyms
Name of Substance
- Bismuth subsalicylate
- Bismuth subsalicylate [USAN:USP:JAN]
Synonyms
- 2-Hydroxybenzoic acid bismuth (3+) salt, basic
- Basic bismuth salicylate
- Bismogenol tosse inj
- Bismuth oxysalicylate
- Bismuth salicylate, basic
- Bismuth subsalicylate
- Bismuth, (2-hydroxybenzoato-O(1),O(2))oxo-
- Bismuth, oxo(salicylato)-
- Bismuthi subsalicylas
- Bismutum subsalicylicum
- CCRIS 4751
- EC 238-953-1
- EINECS 238-953-1
- HSDB 332
- Kaopectate
- Pepto-Bismol
- Salicylic acid basic bismuth salt
- Salicylic acid, bismuth basic salt
- Spiromak forte
- Stabisol
- Trigastronol
- UNII-62TEY51RR1
- Vismut
- Wismutsalicylat, basisches
- Wismutsubsalicylat
Systematic Names
- (2-Hydroxybenzoato-O(sup 1))-oxobismuth
- 4H-1,3,2-Benzodioxabismin-4-one, 2-hydroxy-
- Bismuth oxide salicylate
- Bismuth subsalicylate
- Bismuth, (2-hydroxybenzoato-O1,O2)oxo- (9CI)
- Bismuth, oxo(salicylato)-
Mixture Name
- Helidac
Registry Numbers
CAS Registry Number
- 14882-18-9
FDA UNII
- 62TEY51RR1
Other Registry Numbers
- 55200-42-5
- 56029-89-1
- 61529-49-5
- 8045-18-9
- 87-27-4
System Generated Number
- 0014882189
Structure Descriptors
InChI
1S/C7H6O3.Bi.H2O/c8-6-4-2-1-3-5(6)7(9)10;;/h1-4,8H,(H,9,10);;1H2/q;+3;/p-3InChIKey
ZREIPSZUJIFJNP-UHFFFAOYSA-KSmiles
c12c(O[Bi](O)Toxicity
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| man | LDLo | intramuscular | 60mg/kg/26W-I (60mg/kg) | KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" | American Journal of Clinical Pathology. Vol. 14, Pg. 392, 1944. |
| man | TDLo | intramuscular | 17mg/kg/5W-I (17mg/kg) | GASTROINTESTINAL: OTHER CHANGES | American Journal of Syphilis, Gonorrhea and Venereal Diseases. Vol. 26, Pg. 84, 1942. |
| women | TDLo | intramuscular | 14480ug/kg/9D (14.48mg/kg) | Archives of Dermatology and Syphilology. Vol. 41, Pg. 1076, 1940. | |
| women | TDLo | intramuscular | 14480ug/kg/9D (14.48mg/kg) | MUSCULOSKELETAL: JOINTS SKIN AND APPENDAGES (SKIN): "DERMATITIS, ALLERGIC: AFTER SYSTEMIC EXPOSURE" | Archives of Dermatology and Syphilology. Vol. 41, Pg. 1076, 1940. |
Physical Properties
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| log P (octanol-water) | 2.460 | (none) | EST | |
| Water Solubility | 44 | mg/L | 25 | EST |
| Vapor Pressure | 6.07E-06 | mm Hg | 25 | EST |
| Atmospheric OH Rate Constant | 2.09E-11 | cm3/molecule-sec | 25 | EST |
Physical property data is provided to ChemIDplus by SRC, Inc.