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Substance Name: Diperdipine hydrochloride
RN: 149543-07-7
UNII: M20H45P1X1
InChIKey: GRDAOFITFJWKFJ-UHFFFAOYSA-N
Classification Code
- Drug / Therapeutic Agent
Molecular Formula
- C24-H31-N3-O6.Cl-H
Molecular Weight
- 493.9848
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Names and Synonyms
Name of Substance
- Diperdipine hydrochloride
Synonyms
- Diperdipine
- UNII-M20H45P1X1
Systematic Name
- 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl 2-(1-piperidinyl)ethyl ester, monohydrochloride
Registry Numbers
CAS Registry Number
- 149543-07-7
FDA UNII
- M20H45P1X1
System Generated Number
- 0149543077
Molecular Formulas
Molecular Formula
- C24-H31-N3-O6.Cl-H
Molecular Formula Fragments
- C24-H31-N3-O6
- Cl-H
- COMPONENT
Structure Descriptors
InChI
1S/C24H31N3O6.ClH/c1-4-32-23(28)20-16(2)25-17(3)21(22(20)18-9-8-10-19(15-18)27(30)31)24(29)33-14-13-26-11-6-5-7-12-26;/h8-10,15,22,25H,4-7,11-14H2,1-3H3;1HInChIKey
GRDAOFITFJWKFJ-UHFFFAOYSA-NSmiles
CCOC(=O)Toxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intravenous | 11420ug/kg (11.42mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Arzneimittel-Forschung. Drug Research. Vol. 45, Pg. 240, 1995. |
mouse | LD50 | oral | 293mg/kg (293mg/kg) | BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: CYANOSIS | Arzneimittel-Forschung. Drug Research. Vol. 45, Pg. 240, 1995. |
rat | LD50 | intravenous | 11730ug/kg (11.73mg/kg) | BEHAVIORAL: MUSCLE WEAKNESS SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Arzneimittel-Forschung. Drug Research. Vol. 45, Pg. 240, 1995. |
rat | LD50 | oral | 363mg/kg (363mg/kg) | LUNGS, THORAX, OR RESPIRATION: DYSPNEA SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Arzneimittel-Forschung. Drug Research. Vol. 45, Pg. 240, 1995. |