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Substance Name: D-Epinephrine
RN: 150-05-0
UNII: NA71GR3TNV
InChIKey: UCTWMZQNUQWSLP-SECBINFHSA-N

Classification Code

  • Drug / Therapeutic Agent

Molecular Formula

  • C9-H13-N-O3

Molecular Weight

  • 183.2057
 
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Names and Synonyms

Results Name

  • D-Epinephrine

Name of Substance

  • Racepinefrine, (S)-

Synonyms

  • 2-13-00-00525 (Beilstein Handbook Reference)
  • BRN 2938799
  • d-Adrenaline
  • D-Epinephrine
  • EINECS 205-752-5
  • L-(+)-Adrenaline
  • UNII-NA71GR3TNV

Systematic Names

  • (S)-4-(1-Hydroxy-2-(methylamino)ethyl)pyrocatechol
  • Benzyl alcohol, 3,4-dihydroxy-alpha-((methylamino)methyl)-, (+)-

Registry Numbers

CAS Registry Number

  • 150-05-0

FDA UNII

  • NA71GR3TNV

System Generated Number

  • 0000150050

Structure Descriptors

InChI

1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m1/s1

InChIKey

UCTWMZQNUQWSLP-SECBINFHSA-N

Smiles

CNC[C@@H](O)c1ccc(O)c(O)c1

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 500ug/kg (0.5mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1294, 1935.
dog LDLo intravenous 1mg/kg (1mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1294, 1935.
dog LDLo subcutaneous 5mg/kg (5mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1294, 1935.
frog LDLo subcutaneous 5gm/kg (5000mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1294, 1935.
guinea pig LDLo subcutaneous 1mg/kg (1mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1294, 1935.
mouse LD50 intravenous 38mg/kg (38mg/kg) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: "INFLAMMATION, NECROSIS, OR SCARRING OF BLADDER"

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 502, 1949.
mouse LD50 subcutaneous 22530ug/kg (22.53mg/kg)   Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 202, Pg. 658, 1943.
rabbit LDLo intravenous 50ug/kg (0.05mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1294, 1935.
rabbit LDLo subcutaneous 10mg/kg (10mg/kg)   "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1294, 1935.
rat LD50 intravenous 800ug/kg (0.8mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Journal of Pharmacology and Experimental Therapeutics. Vol. 95, Pg. 502, 1949.
rat LDLo subcutaneous 80mg/kg (80mg/kg) LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: MUSCLE WEAKNESS

LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
Journal of Physiology. Vol. 38, Pg. 259, 1909.