Skip Navigation
ChemIDplus A TOXNET DATABASE LiteBrowseAdvanced

Substance Name: Procyclidine hydrochloride [USP]
RN: 1508-76-5
UNII: CQC932Z7YW
InChIKey: ZFSPFXJSEHCTTR-UHFFFAOYSA-N

Note

  • A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism.

Molecular Formula

  • C19-H29-N-O.Cl-H

Molecular Weight

  • 323.905
 

Classification Codes

  • Antiparkinsonian
  • Drug / Therapeutic Agent
  • Relaxant (Skeletal Muscle)
* denotes mobile formatted website

Links to Resources


Search for this InChIKey on the Web

Names and Synonyms

Name of Substance

  • Procyclidine hydrochloride [USP]

Synonyms

  • (+-)-Procyclidine hydrochloride
  • 1-cyclohexyl-1-phenyl-3-pyrrolidino-1-propanol hydrochloride
  • alpha-Cyclohexyl-alpha-phenyl-1-pyrrolidinepropanol hydrochloride
  • Arpicolin
  • EINECS 216-141-8
  • Kemadrin
  • Osnervan
  • Procyclidine HCl
  • Procyclidine hydrochloride
  • Tricyclamol hydrochloride
  • UNII-CQC932Z7YW

Systematic Names

  • 1-Pyrrolidinepropanol, alpha-cyclohexyl-alpha-phenyl-, hydrochloride
  • 1-Pyrrolidinepropanol, alpha-cyclohexyl-alpha-phenyl-, monohydrochloride
  • Procyclidine hydrochloride

Registry Numbers

CAS Registry Number

  • 1508-76-5

FDA UNII

  • CQC932Z7YW

Other Registry Number

  • 30953-84-5

System Generated Number

  • 0001508765

Molecular Formulas

Molecular Formula

  • C19-H29-N-O.Cl-H

Molecular Formula Fragments

  • C19-H29-N-O
  • Cl-H
  • COMPONENT

Structure Descriptors

InChI

1S/C19H29NO.ClH/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20;/h1,3-4,9-10,18,21H,2,5-8,11-16H2;1H

InChIKey

ZFSPFXJSEHCTTR-UHFFFAOYSA-N

Smiles

c1ccc(cc1)C(CCN2CCCC2)(C3CCCCC3)O.Cl

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 14mg/kg (14mg/kg) BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
British Journal of Pharmacology and Chemotherapy. Vol. 10, Pg. 383, 1955.
mouse LD50 intravenous 55mg/kg (55mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 103, Pg. 100, 1955.