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Substance Name: Sodium lauryl sulfate [JAN:NF]
RN: 151-21-3
UNII: 368GB5141J
InChIKey: DBMJMQXJHONAFJ-UHFFFAOYSA-M

Note

  • An anionic surfactant, usually a mixture of sodium alkyl sulfates, mainly the lauryl; lowers surface tension of aqueous solutions; used as fat emulsifier, wetting agent, detergent in cosmetics, pharmaceuticals and toothpastes; also as research tool in protein biochemistry.

Molecular Formula

  • C12-H26-O4-S.Na

Molecular Weight

  • 288.3815
 

Classification Codes

  • Drug / Therapeutic Agent
  • Mutation Data
  • Pharmaceutic Aid (Surfactant)
  • Reproductive Effect
  • Skin / Eye Irritant
  • Surface-Active Agents

Names and Synonyms

Name of Substance

  • Sodium dodecyl sulfate
  • Sodium lauryl sulfate
  • Sodium lauryl sulfate [JAN:NF]

MeSH Heading

  • Sodium dodecyl sulfate

Synonyms

  • AI3-00356
  • Akyposal SDS
  • Anticerumen
  • Aquarex ME
  • Aquarex methyl
  • Avirol 101
  • Avirol 118 conc
  • Berol 452
  • Carsonol SLS
  • Carsonol SLS Paste B
  • Carsonol SLS Special
  • Caswell No. 779
  • CCRIS 6272
  • Conco sulfate WA
  • Conco sulfate WA-1200
  • Conco sulfate WA-1245
  • Conco Sulfate WAG
  • Conco Sulfate WAN
  • Conco Sulfate WAS
  • Conco sulfate WN
  • CP 75424
  • Cycloryl 21
  • Cycloryl 31
  • Cycloryl 580
  • Cycloryl 585N
  • Dehydag sulfate GL emulsion
  • Dehydag sulphate GL emulsion
  • Dehydrag sulfate gl emulsion
  • Detergent 66
  • Dodecyl alcohol, hydrogen sulfate, sodium salt
  • Dodecyl sodium sulfate
  • Dodecyl sulfate sodium
  • Dodecyl sulfate, sodium salt
  • Dreft
  • Dupanol WAQ
  • Duponal
  • Duponal WAQE
  • Duponol
  • Duponol C
  • Duponol ME
  • Duponol methyl
  • Duponol QC
  • Duponol QX
  • Duponol WA
  • Duponol WA Dry
  • Duponol WAQ
  • Duponol WAQA
  • Duponol WAQE
  • Duponol WAQM
  • EC 205-788-1
  • EINECS 205-788-1
  • EMAL 10
  • EMAL O
  • Emersal 6400
  • Empicol LPZ
  • Empicol LS 30
  • Empicol LX 28
  • Emulsifier No. 104
  • EPA Pesticide Chemical Code 079011
  • Finasol osr(sub 2)
  • Finasol osr2
  • Gardinol
  • Hexamol SLS
  • HSDB 1315
  • Incronol SLS
  • Irium
  • Jordanol SL-300
  • Lanette wax-S
  • Lauryl sodium sulfate
  • Lauryl sulfate, sodium salt
  • Laurylsiran sodny
  • Laurylsiran sodny [Czech]
  • Lauyl sodium sulfate
  • Maprobix NEU
  • Maprofix 563
  • Maprofix LK
  • Maprofix NEU
  • Maprofix WAC
  • Maprofix wac-LA
  • Melanol CL
  • Melanol CL 30
  • Monagen Y 100
  • Monododecyl sodium sulfate
  • Monogen Y 100
  • Montopol LA paste
  • n-Dodecyl sulfate sodium
  • NALS
  • Natrium laurylsulfuricum
  • Natriumlaurylsulfat
  • NCI-C50191
  • Neutrazyme
  • Nikkol SLS
  • NSC 402488
  • Odoripon AL 95
  • Orvus WA paste
  • P and G emulsifier 104
  • Perklankrol ESD 60
  • Perlandrol L
  • Perlankrol L
  • Product No. 161
  • Product No. 75
  • Quolac EX-UB
  • Rewopol NLS 30
  • Richonol A
  • Richonol AF
  • Richonol C
  • SDS
  • Sinnopon LS 100
  • Sinnopon LS 95
  • Sintapon L
  • Sipex OP
  • Sipex SB
  • Sipex SD
  • Sipex SP
  • Sipex UB
  • Sipon LS
  • Sipon LS 100
  • Sipon LSB
  • Sipon PD
  • Sipon WD
  • SLS
  • Sodium dodecyl sulfate
  • Sodium dodecyl sulphate
  • Sodium dodecylsulfate
  • Sodium lauryl sulfate
  • Sodium lauryl sulfate 30%
  • Sodium lauryl sulfate ether
  • Sodium lauryl sulfate, dental grade
  • Sodium lauryl sulphate
  • Sodium monododecyl sulfate
  • Sodium monolauryl sulfate
  • Sodium n-dodecyl sulfate
  • Sodiumlauryl ether sulfate
  • Solsol needles
  • Standapol 112 conc
  • Standapol WA-AC
  • Standapol WAQ
  • Standapol WAQ Special
  • Standapol WAS 100
  • Steinapol NLS 90
  • Stepanol ME
  • Stepanol ME Dry
  • Stepanol ME Dry AW
  • Stepanol methyl
  • Stepanol methyl dry AW
  • Stepanol T 28
  • Stepanol WA
  • Stepanol WA paste
  • Stepanol WA-100
  • Stepanol WAC
  • Stepanol WAQ
  • Sterling WA paste
  • Sterling WAQ-CH
  • UNII-368GB5141J

Systematic Names

  • Sodium dodecyl sulfate
  • Sodium dodecyl sulphate
  • Sulfuric acid monododecyl ester sodium salt
  • Sulfuric acid monododecyl ester sodium salt (1:1)

Superlist Names

  • Dodecyl sulfate, sodium salt
  • Sodium lauryl sulfate
  • Sulfuric acid monododecyl ester sodium salt

Registry Numbers

CAS Registry Number

  • 151-21-3

FDA UNII

  • 368GB5141J

Other Registry Numbers

  • 1000201-72-8
  • 1000201-73-9
  • 111726-87-5
  • 121481-64-9
  • 12738-53-3
  • 12765-21-8
  • 129203-37-8
  • 1334-67-4
  • 1335-72-4
  • 145269-44-9
  • 152155-52-7
  • 156108-01-9
  • 172826-72-1
  • 1883428-81-6
  • 191490-40-1
  • 210297-21-5
  • 237743-45-2
  • 303179-49-9
  • 39384-36-6
  • 51222-39-0
  • 57176-54-2
  • 58640-35-0
  • 61711-39-5
  • 64441-33-4
  • 74433-77-5
  • 8012-56-4
  • 8048-56-4
  • 877454-24-5
  • 952055-37-7
  • 952092-90-9

System Generated Number

  • 0000151213

Molecular Formulas

Molecular Formula

  • C12-H26-O4-S.Na

Molecular Formula Fragments

  • C12-H26-O4-S
  • COMPONENT
  • Na

Structure Descriptors

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChIKey

DBMJMQXJHONAFJ-UHFFFAOYSA-M

Smiles

C(CCCCCCCCCC)COS(=O)(=O)[O-].[Na+]

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 250mg/kg (250mg/kg) VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION

BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 283, 1953.
mouse LD50 intravenous 118mg/kg (118mg/kg)   Journal of Pharmaceutical Sciences. Vol. 52, Pg. 803, 1963.
rabbit LDLo skin 10gm/kg (10000mg/kg) GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

BEHAVIORAL: ATAXIA
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 23-3/1971,
rat LC50 inhalation > 3900mg/m3/1H (3900mg/m3)   BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 23-3/1971,
rat LD50 intraperitoneal 210mg/kg (210mg/kg)   Proceedings of the Scientific Section of the Toilet Goods Association. Vol. 3, Pg. 1, 1945.
rat LD50 intravenous 118mg/kg (118mg/kg)   Journal of Pharmaceutical Sciences. Vol. 52, Pg. 803, 1963.
rat LD50 oral 1288mg/kg (1288mg/kg)   Food and Cosmetics Toxicology. Vol. 5, Pg. 763, 1967.

Physical Properties

Physical Property Value Units Temp (deg C) Source
Melting Point 205.5 deg C   EXP
log P (octanol-water) 1.6 (none)   EXP
Water Solubility 1.00E+05 mg/L   EXP
Vapor Pressure 4.70E-13 mm Hg 25 EST
Atmospheric OH Rate Constant 1.48E-11 cm3/molecule-sec 25 EST

Physical property data is provided to ChemIDplus by SRC, Inc.