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Substance Name: Potassium cyanide
RN: 151-50-8
UNII: MQD255M2ZO
InChIKey: YUZRZFQHUCKACF-UHFFFAOYSA-N
Note
- A highly poisonous compound that is an inhibitor of many metabolic processes, but has been shown to be an especially potent inhibitor of heme enzymes and hemeproteins. It is used in many industrial processes.
Molecular Formula
- C-K-N
Molecular Weight
- 65.116
Classification Codes
Classification Codes
- Enzyme Inhibitors
- Human Data
- Mutation Data
- Noxae
- Poisons
- Reproductive Effect
Superlist Classification Codes
- Ceiling 5 mg/m3; skin
- Reportable Quantity (RQ) = 10 lb
- Threshold Planning Quantity (TPQ) = 100 lb
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Names and Synonyms
Name of Substance
- Potassium cyanide
MeSH Heading
- Potassium cyanide
Synonyms
- 4-02-00-00050 (Beilstein Handbook Reference)
- AI3-28749
- BRN 4652394
- Caswell No. 688A
- Cyanide of potassium
- Cyanure de potassium
- Cyanure de potassium [French]
- EC 205-792-3
- EINECS 205-792-3
- EPA Pesticide Chemical Code 599600
- HSDB 1245
- Hydrocyanic acid, potassium salt
- Kalium cyanid
- Kalium cyanid [German]
- M-44 capsules (potassium cyanide)
- Potassium cyanide
- Potassium cyanide (K(CN))
- RCRA waste number P098
- UNII-MQD255M2ZO
Systematic Names
- Potassium cyanide
- Potassium cyanide (K(CN))
Superlist Names
- Cyanide salts
- Hydrogen cyanide and cyanide salts
- Potassium cyanide
- Potassium cyanide K(CN)
- Potassium cyanide [UN1680] [Poison]
- RCRA waste no. P098
- UN1680
Registry Numbers
CAS Registry Number
- 151-50-8
FDA UNII
- MQD255M2ZO
Other Registry Numbers
- 133708-36-8
- 15745-74-1
- 60195-52-0
System Generated Number
- 0000151508
Structure Descriptors
InChI
InChI=1S/CN.K/c1-2;InChIKey
YUZRZFQHUCKACF-UHFFFAOYSA-NSmiles
[K]C#NToxicity
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LD50 | intravenous | 2200ug/kg (2.2mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 35, Pg. 316, 1936. | |
dog | LD50 | subcutaneous | 6mg/kg (6mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Archiv fuer Toxikologie. Vol. 21, Pg. 89, 1965. |
dog | LDLo | intravenous | 5mg/kg (5mg/kg) | "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 209, 1973. | |
frog | LDLo | subcutaneous | 60mg/kg (60mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 3, Pg. 77, 1897. | |
guinea pig | LDLo | intraarterial | 5mg/kg (5mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928. | |
guinea pig | LDLo | intraperitoneal | 8mg/kg (8mg/kg) | Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 96, Pg. 202, 1927. | |
guinea pig | LDLo | intravenous | 5mg/kg (5mg/kg) | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 131, Pg. 171, 1928. | |
guinea pig | LDLo | subcutaneous | 8mg/kg (8mg/kg) | Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 96, Pg. 202, 1927. | |
human | LDLo | oral | 2857ug/kg (2.857mg/kg) | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 191, 1969. | |
man | TDLo | oral | 13699ug/kg (13.699mg/kg) | BEHAVIORAL: COMA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Journal of Toxicology, Clinical Toxicology. Vol. 25, Pg. 121, 1987. |
mouse | LD50 | intraperitoneal | 5991ug/kg (5.991mg/kg) | Pesticide Biochemistry and Physiology. Vol. 2, Pg. 95, 1972. | |
mouse | LD50 | intravenous | 2600ug/kg (2.6mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) | Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954. |
mouse | LD50 | oral | 8500ug/kg (8.5mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 161, Pg. 163, 1968. | |
mouse | LD50 | subcutaneous | 6500ug/kg (6.5mg/kg) | Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. Vol. 54, Pg. 1057, 1958. | |
pigeon | LD50 | intramuscular | 4mg/kg (4mg/kg) | Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954. | |
rabbit | LD50 | intramuscular | 3256ug/kg (3.256mg/kg) | Journal of the American College of Toxicology. Vol. 1(3), Pg. 120, 1982. | |
rabbit | LD50 | intraperitoneal | 3972ug/kg (3.972mg/kg) | BLOOD: OTHER CHANGES | Toxicologist. Vol. 3, Pg. 64, 1983. |
rabbit | LD50 | ocular | 7870ug/kg (7.87mg/kg) | BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE | Journal of Toxicology, Cutaneous and Ocular Toxicology. Vol. 2, Pg. 119, 1983. |
rabbit | LD50 | oral | 5mg/kg (5mg/kg) | "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 209, 1973. | |
rabbit | LD50 | subcutaneous | 4mg/kg (4mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954. |
rat | LD50 | intraperitoneal | 4mg/kg (4mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Journal of Applied Physiology. Vol. 32, Pg. 315, 1972. |
rat | LD50 | intravenous | 3600ug/kg (3.6mg/kg) | BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Drug Development Research. Vol. 5, Pg. 225, 1985. |
rat | LD50 | oral | 5mg/kg (5mg/kg) | Archives of Toxicology. Vol. 54, Pg. 275, 1983. | |
rat | LD50 | subcutaneous | 7814ug/kg (7.814mg/kg) | Archives of Toxicology, Supplement. Vol. 14, Pg. 231, 1991. | |
rat | LDLo | intramuscular | 8mg/kg (8mg/kg) | "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973Vol. -, Pg. 209, 1973. | |
women | TDLo | oral | 100mg/kg (100mg/kg) | VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | American Journal of Emergency Medicine. Vol. 1, Pg. 94, 1983. |