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Substance Name: Cerliponase alfa [USAN:INN]
RN: 151662-36-1
UNII: X8R2D92QP1

Note

  • Releases N-terminal tripeptides from polypeptides; involved in the degradation of bone collagen; mutations in gene are associated with the Late-Infantile Neuronal Ceroid Lipofuscinosis (LINCL); RefSeq NM_000391 (human); NM_009906 (mouse); NM_031357 (rat).

Molecular Formula

  • C2657-H4042-N734-O793-S11

Molecular Weight

  • 59308.2298
 

Classification Code

  • Treatment of Neurological Genetic Disorders
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Links to Resources

Names and Synonyms

Name of Substance

  • Cerliponase alfa [USAN:INN]
  • Tripeptidyl-peptidase 1

Synonyms

  • Brineura
  • Cerliponase alfa
  • Cerliponase alfa [INN]
  • CLN2 protein
  • E.C. 3.4.14.8
  • E.C. 3.4.14.9
  • Immature cell growth-inhibiting gene 1 protein
  • Immature human tripeptidyl-peptidase 1
  • Immature lysosomal pepstatin-insensitive protease
  • Immature tripeptidyl-peptidase I
  • Pepinase
  • Tripeptidyl aminopeptidase
  • Tripeptidyl peptidase 1
  • Tripeptidyl peptidase I
  • UNII-X8R2D92QP1

Systematic Name

  • Tripeptidyl aminopeptidase I

Registry Numbers

CAS Registry Number

  • 151662-36-1

FDA UNII

  • X8R2D92QP1

Other Registry Numbers

  • 227604-61-7
  • 227951-49-7

System Generated Number

  • 0151662361